General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 4775 |
Name | NFATC3 |
Synonymous | NFAT4|NFATX;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3;NFATC3;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
Definition | NF-ATc3|T cell transcription factor NFAT4|nuclear factor of activated T-cells c3 isoform IE-Xa|nuclear factor of activated T-cells, cytoplasmic 3 |
Position | 16q22.2 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr16:68118654-68263162 | chr16:68127278-68127278 | rs1074143 | Single_Nucleotides|eQTL|RLTPR, Chromatin_Structure|DNase-seq|Hl60 | chr16:68118654-68263162 | chr16:68136622-68136622 | rs8058690 | Single_Nucleotides|eQTL|RLTPR, Chromatin_Structure|DNase-seq|Gm06990, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1 | chr16:68118654-68263162 | chr16:68150527-68150527 | rs12447640 | Single_Nucleotides|eQTL|RLTPR, Motifs|PWM|Zscan4, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Nhdfad, Chromatin_Structure|DNase-seq|Hasp, Protein_Binding|ChIP-seq|CTCF | chr16:68118654-68263162 | chr16:68152035-68152035 | rs12599880 | Single_Nucleotides|eQTL|RLTPR, Chromatin_Structure|DNase-seq|Gm12865 |
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Transcription Factors [Top] |
Regulation From TransFac database |
NF-AT4(h) + CKI-alpha(h) <==> NF-AT4(h):CKI-alpha(h) (binding) | JNK2(h) + NF-AT4(h) <==> JNK2(h):NF-AT4(h) (binding) | NF-AT4(h) + calcineurin(r) <==> NF-AT4(h):calcineurin(r) (binding) | NF-AT4(h) + SRC3(h) <==> NF-AT4(h):SRC3(h) (binding) | NF-AT4(h) --> Acta2(m) (DNA binding). | NFATC3(h) --> NF-AT4(h) (expression). | NF-AT4(h) --> Il2(m) (DNA binding). | NF-AT4(h) --> IL-5(m) (DNA binding). | NF-AT4(h) --> NPPB(h) (DNA binding). | NF-AT4(h) --> IL2(h) (DNA binding). | NF-AT4(h) --> Sftpd(m) (DNA binding; transactivation). | NFATC3(h) --> NF-AT4(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
163 | Phosphoserine (MAPK9) | 9374467 | Phospho.ELM 6.0 | 165 | Phosphoserine (MAPK9) | 9374467 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr16 |
Promoter: 66675376 - 66677376 | Agilent_014791 |
chr16 |
Promoter: 66675376 - 66677376 | GSE27584 |
chr16 |
Promoter: 66675376 - 66677376 | GSE27584 |
chr16 |
Promoter: 66675376 - 66677376 | GSE27584 |
chr16 |
Promoter: 66675376 - 66677376 | GSE27584 |
chr16 |
Promoter: 66675376 - 66677376 | Agilent_014791 |