| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 4791 |
Name | NFKB2 |
Synonym | H2TF1|LYT-10|LYT10|NF-kB2|p105|p52;nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100);NFKB2;nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
Definition | DNA-binding factor KBF2|lymphocyte translocation chromosome 10 protein|nuclear factor NF-kappa-B p100 subunit|nuclear factor of kappa light chain gene enhancer in B-cells 2|oncogene Lyt-10 |
Position | 10q24 |
Gene Type | protein-coding |
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PAH Type |
Description |
PH | A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats. |
| More detail of all Rat literatures about NFKB2 | |
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Pathways and Diseases |
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Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | B cell activation;PANTHER;P00010 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | T cell activation;PANTHER;P00053 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Alternative NF-kappaB pathway;PID Curated;200037 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Toll receptor signaling pathway;PANTHER;P00054 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
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External Links |
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Links to Entrez Gene | 4791 |
Links to all GeneRIF Items | 4791 |
Links to iHOP | 4791 |
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Sequence Information |
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Nucleotide Sequence |
>4791 : length: 2700 atggagagttgctacaacccaggtctggatggtattattgaatatgatgatttcaaattg aactcctccattgtggaacccaaggagccagccccagaaacagctgatggcccctacctg gtgatcgtggaacagcctaagcagagaggcttccgatttcgatatggctgtgaaggcccc tcccatggaggactgcccggtgcctccagtgagaagggccgaaagacctatcccactgtc aagatctgtaactacgagggaccagccaagatcgaggtggacctggtaacacacagtgac ccacctcgtgctcatgcccacagtctggtgggcaagcaatgctcggagctggggatctgc gccgtttctgtggggcccaaggacatgactgcccaatttaacaacctgggtgtcctgcat gtgactaagaagaacatgatggggactatgatacaaaaacttcagaggcagcggctccgc tctaggccccagggccttacggaggccgagcagcgggagctggagcaagaggccaaagaa ctgaagaaggtgatggatctgagtatagtgcggctgcgcttctctgccttccttagagcc agtgatggctccttctccctgcccctgaagccagtcatctcccagcccatccatgacagc aaatctccgggggcatcaaacctgaagatttctcgaatggacaagacagcaggctctgtg cggggtggagatgaagtttatctgctttgtgacaaggtgcagaaagatgacattgaggtt cggttctatgaggatgatgagaatggatggcaggcctttggggacttctctcccacagat gtgcataaacagtatgccattgtgttccggacacccccctatcacaagatgaagattgag cggcctgtaacagtgtttctgcaactgaaacgcaagcgaggaggggacgtgtctgattcc aaacagttcacctattaccctctggtggaagacaaggaagaggtgcagcggaagcggagg aaggccttgcccaccttctcccagcccttcgggggtggctcccacatgggtggaggctct gggggtgcagccgggggctacggaggagctggaggaggtggcagcctcggtttcttcccc tcctccctggcctacagcccctaccagtccggcgcgggccccatgggctgctacccggga ggcgggggcggggcgcagatggccgccacggtgcccagcagggactccggggaggaagcc gcggagccgagcgccccctccaggaccccccagtgcgagccgcaggccccggagatgctg cagcgagctcgagagtacaacgcgcgcctgttcggcctggcgcagcgcagcgcccgagcc ctactcgactacggcgtcaccgcggacgcgcgcgcgctgctggcgggacagcgccacctg ctgacggcgcaggacgagaacggagacacaccactgcacctagccatcatccacgggcag accagtgtcattgagcagatagtctatgtcatccaccacgcccaggacctcggcgttgtc aacctcaccaaccacctgcaccagacgcccctgcacctggcggtgatcacggggcagacg agtgtggtgagctttctgctgcgggtaggtgcagacccagctctgctggatcggcatgga gactcagccatgcatctggcgctgcgggcaggcgctggtgctcctgagctgctgcgtgca ctgcttcagagtggagctcctgctgtgccccagctgttgcatatgcctgactttgaggga ctgtatccagtacacctggcggtccgagcccgaagccctgagtgcctggatctgctggtg gacagtggggctgaagtggaggccacagagcggcaggggggacgaacagccttgcatcta gccacagagatggaggagctggggttggtcacccatctggtcaccaagctccgggccaac gtgaacgctcgcacctttgcgggaaacacacccctgcacctggcagctggactggggtac ccgaccctcacccgcctccttctgaaggctggtgctgacatccatgctgaaaacgaggag cccctgtgcccactgccttcaccccctacctctgatagcgactcggactctgaagggcct gagaaggacacccgaagcagcttccggggccacacgcctcttgacctcacttgcagcacc aaggtgaagaccttgctgctaaatgctgctcagaacaccatggagccacccctgaccccg cccagcccagcagggccgggactgtcacttggtgatacagctctgcagaacctggagcag ctgctagacgggccagaagcccagggcagctgggcagagctggcagagcgtctggggctg cgcagcctggtagacacgtaccgacagacaacctcacccagtggcagcctcctgcgcagc tacgagctggctggcggggacctggcaggtctactggaggccctgtctgacatgggccta gaggagggagtgaggctgctgaggggtccagaaacccgagacaagctgcccagcacagag gtgaaggaagacagtgcgtacgggagccagtcagtggagcaggaggcagagaagctgggc ccaccccctgagccaccaggagggctctgccacgggcacccccagcctcaggtgcactga |
Protein Sequence |
>4791 : length: 899 MESCYNPGLDGIIEYDDFKLNSSIVEPKEPAPETADGPYLVIVEQPKQRGFRFRYGCEGP SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGIC AVSVGPKDMTAQFNNLGVLHVTKKNMMGTMIQKLQRQRLRSRPQGLTEAEQRELEQEAKE LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS GGAAGGYGGAGGGGSLGFFPSSLAYSPYQSGAGPMGCYPGGGGGAQMAATVPSRDSGEEA AEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAGQRHL LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT SVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN VNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGP EKDTRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLGDTALQNLEQ LLDGPEAQGSWAELAERLGLRSLVDTYRQTTSPSGSLLRSYELAGGDLAGLLEALSDMGL EEGVRLLRGPETRDKLPSTEVKEDSAYGSQSVEQEAEKLGPPPEPPGGLCHGHPQPQVH |