| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 51385 |
Name | ZNF589 |
Synonym | SZF1;zinc finger protein 589;ZNF589;zinc finger protein 589 |
Definition | KRAB-zinc finger protein SZF1-1|stem cell zinc finger protein 1 |
Position | 3p21 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about ZNF589 | |
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External Links |
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Links to Entrez Gene | 51385 |
Links to all GeneRIF Items | 51385 |
Links to iHOP | 51385 |
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Sequence Information |
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Nucleotide Sequence |
>51385 : length: 1095 atgtgggccccgcgggagcagctactgggctggactgcggaagctctgcctgccaaggat tctgcctggccctgggaagagaagcctagatatctgggaccagtgactttcgaggatgtg gctgtgcttttcactgaggcagagtggaagagactgagccttgagcagaggaacctatac aaagaagtgatgctggaaaatctcaggaatctggtctcattggcagaatcaaagccagaa gtccatacctgcccttcttgccctctggcctttggcagtcagcagttcctcagccaagat gagctacacaatcatcctattccaggtttccatgcaggaaatcaactccacccaggaaat ccctgcccagaggatcagccacagtcacaacatccttctgataaaaatcacaggggggct gaagcagaagatcaacgagtggaaggaggcgtcagacccttgttttggagtacaaatgaa aggggggctttagtgggtttctctagcctgttccagagaccaccaataagctcttgggga ggcaacagaatattagagatacagctcagtccagcccagaatgcaagctctgaggaagta gacagaatttccaagagggcagaaaccccagggtttggagcagtcacgtttggggagtgt gcactagcttttaaccagaagtcaaacctgttcagacagaaggcagtcacagcagaaaaa tcttcagacaaaaggcagtcacaggtgtgcagggagtgtgggcgaggctttagcaggaag tcacagctcatcatacaccagaggacacacacaggagaaaagccttatgtctgcggagag tgtgggcgaggctttatagttgagtcagtcctccgcaaccacctgagtacacactccggg gagaaaccttatgtgtgcagccattgtgggcgaggctttagctgcaagccatacctcatc agacatcagaggacacacacaagggagaaatcgtttatgtgcacagtgtgtgggcgaggc tttcgtgaaaagtcagagctcattaagcaccagagaattcacacgggggataagccttat gtgtgcagagattga |
Protein Sequence |
>51385 : length: 364 MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLY KEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGN PCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWG GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEK SSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSG EKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPY VCRD |