Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51385

Name

ZNF589

Synonymous

SZF1;zinc finger protein 589;ZNF589;zinc finger protein 589

Definition

KRAB-zinc finger protein SZF1-1|stem cell zinc finger protein 1

Position

3p21

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr3:48282590-48340743chr3:48282695-48282695rs9847953Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Chromatin_Structure|DNase-seq|Huh75, Chromatin_Structure|DNase-seq|Helas3Ifna4h, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|A549, Chromatin_Structure|DNase-seq|Cll, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Stellate, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|DNase-seq|Chorion, Chromatin_Structure|DNase-seq|8988t, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|DNase-seq|H1hesc, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Huvec, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Urotsa, Chromatin_Structure|DNase-seq|Htr8, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Gm18507, Chromatin_Structure|DNase-seq|T47d, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Melano, Chromatin_Structure|DNase-seq|Gliobla, Chromatin_Structure|DNase-seq|Hepg2, Chromatin_Structure|DNase-seq|UrotsaUt189, Chromatin_Structure|DNase-seq|Gm19240, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Ips, Chromatin_Structure|DNase-seq|Panisd, Chromatin_Structure|DNase-seq|Nhek, Chromatin_Structure|DNase-seq|Osteobl, Chromatin_Structure|DNase-seq|H9es, Chromatin_Structure|DNase-seq|Progfib, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|Panislets, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|DNase-seq|Aosmc, Chromatin_Structure|DNase-seq|Fibrobl, Chromatin_Structure|DNase-seq|Myometr, Chromatin_Structure|DNase-seq|K562, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|FAIRE|Urotsa, Chromatin_Structure|DNase-seq|Hpde6e6e7, Chromatin_Structure|FAIRE|Gm12878, Chromatin_Structure|FAIRE|UrotsaUt189, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|FAIRE|Hepg2, Chromatin_Structure|FAIRE|K562, Chromatin_Structure|DNase-seq|Ag10803, Chromatin_Structure|DNase-seq|Hasp, Chromatin_Structure|DNase-seq|Bj, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Panc1, Chromatin_Structure|DNase-seq|Th2, Chromatin_Structure|DNase-seq|Cmk, Chromatin_Structure|FAIRE|Htr8, Chromatin_Structure|DNase-seq|Hepatocytes, Protein_Binding|ChIP-seq|HNF4A, Protein_Binding|ChIP-seq|GATA1, Protein_Binding|ChIP-seq|HNF4A, Protein_Binding|ChIP-seq|E2F1, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|FOS, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|GABPA, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|MAX, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|CHD2, Protein_Binding|ChIP-seq|CHD2, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|E2F6, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|SIN3A, Protein_Binding|ChIP-seq|ZBTB33, Protein_Binding|ChIP-seq|HEY1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TFAP2A, Protein_Binding|ChIP-seq|TFAP2C, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|CCNT2, Protein_Binding|ChIP-seq|HMGN3, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|ZNF263, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|YY1, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|NRF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF7, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|NRF1, Protein_Binding|ChIP-seq|NRF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|MAX, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|PAX5, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|E2F1, Protein_Binding|ChIP-seq|E2F1, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|TRIM28, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|CTCF, Protein_Binding|ChIP-seq|E2F4
chr3:48282590-48340743chr3:48309828-48309828rs11718329Single_Nucleotides|eQTL|NME6, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Chromatin_Structure|FAIRE|Nhek, Chromatin_Structure|DNase-seq|Cll, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Urotsa, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Nhek, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|FAIRE|Nhbe, Chromatin_Structure|DNase-seq|Hpde6e6e7, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Mcf7, Protein_Binding|ChIP-seq|STAT3, Protein_Binding|ChIP-seq|CDX2
chr3:48282590-48340743chr3:48312060-48312060rs6442111Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Chromatin_Structure|DNase-seq|Hepatocytes, Chromatin_Structure|FAIRE|Nhek
chr3:48282590-48340743chr3:48316034-48316034rs6442112Single_Nucleotides|eQTL|NCKIPSD, Single_Nucleotides|eQTL|NCKIPSD, Single_Nucleotides|eQTL|NICN1, Single_Nucleotides|eQTL|WDR6, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|DNase-seq|H1hesc, Chromatin_Structure|DNase-seq|Hepatocytes, Chromatin_Structure|DNase-seq|8988t, Chromatin_Structure|DNase-seq|H7es, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|Ips, Chromatin_Structure|FAIRE|Helas3, Protein_Binding|ChIP-seq|BCL3
chr3:48282590-48340743chr3:48326433-48326433rs6801801Single_Nucleotides|eQTL|NME6, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Chromatin_Structure|DNase-seq|Gm12865
chr3:48282590-48340743chr3:48327450-48327450rs9833309Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Chromatin_Structure|DNase-seq|Bj, Chromatin_Structure|DNase-seq|Ag09309
chr3:48282590-48340743chr3:48339360-48339360rs13079728Single_Nucleotides|eQTL|NME6, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|DNase-seq|Gm12865, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|FAIRE|Gm19239, Protein_Binding|ChIP-seq|YY1
chr3:48282590-48340743chr3:48339699-48339699rs13084616Single_Nucleotides|eQTL|NME6, Single_Nucleotides|eQTL|WDR6, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Single_Nucleotides|eQTL|ZNF589, Motifs|Footprinting|Oct-4(POU5F1), Motifs|PWM|Oct-4(POU5F1), Protein_Binding|ChIP-seq|FOXA1

Transcription Factors   [Top]

Regulation From TransFac database

ZNF589(h) --> SZF1-isoform3(h) (expression).
ZNF589(h) --> SZF1(h) (expression).
ZNF589(h) --> SZF1-isoform2(h) (expression).
ZNF589(h) --> SZF1-isoform1(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for ZNF589

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

 Promoter: 48256149 - 48258149Agilent_014791

chr3

 Promoter: 48256149 - 48258149GSE27584

chr3

 Promoter: 48256149 - 48258149Agilent_014791_44K

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