| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 51517 |
Name | NCKIPSD |
Synonym | AF3P21|DIP|DIP1|ORF1|SPIN90|WASLBP|WISH;NCK interacting protein with SH3 domain;NCKIPSD;NCK interacting protein with SH3 domain |
Definition | 54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein|90 kDa SH3 protein interacting with Nck|DIP-1|NCK-interacting protein with SH3 domain|SH3 adapter protein SPIN90|SH3 protein interacting with Nck, 90 kDa|VIP54|WASP-interacting SH3-domain |
Position | 3p21 |
Gene Type | protein-coding |
|
PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about NCKIPSD | |
|
External Links |
|
Links to Entrez Gene | 51517 |
Links to all GeneRIF Items | 51517 |
Links to iHOP | 51517 |
|
Sequence Information |
|
Nucleotide Sequence |
>51517 : length: 2169 atgtaccgcgcgctgtacgcgttccgctcggcggagcccaacgcgctggcgttcgccgcg ggcgagaccttcctggtgctagagcgaagcagcgcgcactggtggctggccgcgcgggcg cgcagtggtgagacgggctacgtgccgccagcctacctgcgccgcctgcagggcctggag caggatgtcctccaggccattgaccgggccatcgaggctgtacacaacacagccatgcgg gatggtggcaagtacagcctggaacagcgtggagtcctccagaagctgatccaccaccgg aaagagaccctgtcacgcagaggcccttcagcctccagtgttgcagttatgacctcatca accagtgaccaccacttggatgctgctgcagccaggcagcccaatggggtgtgtcgagct gggttcgagcggcagcacagcctacccagttctgagcatcttggggcagatggaggcctc taccagatcccacttccatcttcccagatcccaccacagcctcgccgagcagcacccacc acaccgcccccaccagtgaagcgccgagaccgcgaggccctgatggcctctgggagtggt ggccacaacaccatgccctccgggggtaactctgtgtccagcggctcctcagtcagcagc acctccctggacacgctctataccagctccagcccatctgaaccaggctccagctgctca cccacacccccacctgtgccccgccgaggcacccacaccaccgtgtcccaagtccagccc cctccctccaaggcatcagcacctgaaccccctgcagaagaagaagtggcaactggtaca acctcagcctctgatgacctggaagccctgggtacactgagcctggggaccacagaggag aaggcagcagctgaggcggctgtgcccaggaccattggggccgagctgatggagctggtg cggagaaacactggcctgagccacgaattatgccgggtggccatcggcatcatagtgggt cacatccaggcctcggtgccggccagctcaccagtcatggagcaggtcctcctctcactc gtagagggcaaggacctcagcatggccctgccctcagggcaggtctgccacgaccagcag aggctggaggtgatctttgcagacctggctcgccggaaggacgacgcccagcagcgcagt tgggcactatatgaggatgagggtgtcatccgctgctacctagaggagctgctgcatatt ctgactgatgcagaccctgaagtttgcaagaaaatgtgcaagagaaacgagttcgagtct gtcctggccttggtggcctattaccaaatggaacaccgagcatcactgcggctgctgctc ctcaagtgctttggcgccatgtgcagcctggatgcagccatcatctccacgcttgtgtca tccgtgctgcctgtagagctggcgagggacatgcagacagacacgcaggaccaccagaaa ctctgttactctgccctcatcctggccatggtcttctccatgggagaggcagtgccctat gcacactatgagcacctgggcacgcctttcgcccagttcctactgaacatcgtcgaggat gggctgcccttggacaccacagagcagctgccggacctctgcgtgaacctgcttctggct ctcaacctgcacctgccagctgctgaccagaatgtcatcatggctgccctgagcaaacac gccaatgtcaagatcttctccgagaagctgttgttgctcctgaacagaggggatgaccct gtgcgcatcttcaaacatgagccacagccaccacactctgtcctcaagttcctgcaggac gtgtttggcagcccggccacagctgccatcttctaccacacagacatgatggctctcatt gacatcactgtgcggcacatcgcagacctgtcaccaggagacaagctgcgcatggagtac ctctccctgatgcatgctatagtccgcaccacaccctacctgcagcaccgccaccggcta cccgacctgcaggccatactgcgacgcatcctgaatgaggaggagacctcaccccagtgc cagatggaccgcatgattgtccgagagatgtgcaaggaattcctggtgctgggggaggct cccagctag |
Protein Sequence |
>51517 : length: 722 MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPT TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA PS |