General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
---|---|
Gene ID | 5154 |
Name | PDGFA |
Synonym | PDGF-A|PDGF1;platelet-derived growth factor alpha polypeptide;PDGFA;platelet-derived growth factor alpha polypeptide |
Definition | PDGF A-chain|PDGF subunit A|PDGF-1|platelet-derived growth factor A chain|platelet-derived growth factor alpha chain|platelet-derived growth factor alpha isoform 2 preproprotein|platelet-derived growth factor subunit A |
Position | 7p22 |
Gene Type | protein-coding |
PAH Type |
Description |
PAH | PDGF receptor and its antagonists: role in treatment of PAH. |
More detail of all Human literatures about PDGFA | |
Pathways and Diseases |
|
Pathway | Melanoma;KEGG PATHWAY;hsa05218 |
Pathway | Glioma;KEGG PATHWAY;hsa05214 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Gap junction;KEGG PATHWAY;hsa04540 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | role of pi3k subunit p85 in regulation of actin organization and cell migration;PID BioCarta;100211 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | pdgf signaling pathway;PID BioCarta;100077 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | PDGF signaling pathway;PANTHER;P00047 |
Pathway | Prostate cancer;KEGG PATHWAY;hsa05215 |
Pathway | Ceramide signaling pathway;PID Curated;200100 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | phospholipids as signalling intermediaries;PID BioCarta;100183 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Disease | Cancers of the nervous system;KEGG DISEASE |
Disease | Cancers;KEGG DISEASE |
Disease | Cancers of the lung and pleura;KEGG DISEASE |
Disease | Glioma;KEGG DISEASE;H00042 |
Disease | Cancer;FunDO |
Disease | Endometriosis;FunDO |
Disease | Malignant pleural mesothelioma;KEGG DISEASE;H00015 |
External Links |
|
Links to Entrez Gene | 5154 |
Links to all GeneRIF Items | 5154 |
Links to iHOP | 5154 |
Sequence Information |
|
Nucleotide Sequence |
>5154 : length: 636 atgaggaccttggcttgcctgctgctcctcggctgcggatacctcgcccatgttctggcc gaggaagccgagatcccccgcgaggtgatcgagaggctggcccgcagtcagatccacagc atccgggacctccagcgactcctggagatagactccgtagggagtgaggattctttggac accagcctgagagctcacggggtccatgccactaagcatgtgcccgagaagcggcccctg cccattcggaggaagagaagcatcgaggaagctgtccccgctgtctgcaagaccaggacg gtcatttacgagattcctcggagtcaggtcgaccccacgtccgccaacttcctgatctgg cccccgtgcgtggaggtgaaacgctgcaccggctgctgcaacacgagcagtgtcaagtgc cagccctcccgcgtccaccaccgcagcgtcaaggtggccaaggtggaatacgtcaggaag aagccaaaattaaaagaagtccaggtgaggttagaggagcatttggagtgcgcctgcgcg accacaagcctgaatccggattatcgggaagaggacacgggaaggcctagggagtcaggt aaaaaacggaaaagaaaaaggttaaaacccacctaa |
Protein Sequence |
>5154 : length: 211 MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA TTSLNPDYREEDTGRPRESGKKRKRKRLKPT |