Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5154

Name

PDGFA

Synonymous

PDGF-A|PDGF1;platelet-derived growth factor alpha polypeptide;PDGFA;platelet-derived growth factor alpha polypeptide

Definition

PDGF A-chain|PDGF subunit A|PDGF-1|platelet-derived growth factor A chain|platelet-derived growth factor alpha chain|platelet-derived growth factor alpha isoform 2 preproprotein|platelet-derived growth factor subunit A

Position

7p22

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for PDGFA

Transcription Factors   [Top]

Regulation From TransFac database

PDGFA(h) --> PDGF A(h) (expression).
TNF-alpha{sol}(h) --> PDGF A(h) (increase of secretion)
PDGFA(h) --> PDGF A(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

134N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 525507 - 527507GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 525507 - 527507GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 525507 - 527507GSE27584

chr7

Promoter: 525507 - 527507GSE27584


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