| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 5292 |
Name | PIM1 |
Synonym | PIM;pim-1 oncogene;PIM1;pim-1 oncogene |
Definition | Oncogene PIM1|pim-1 kinase 44 kDa isoform|pim-1 oncogene (proviral integration site 1)|proto-oncogene serine/threonine-protein kinase pim-1|serine/threonine-protein kinase pim-1 |
Position | 6p21.2 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. |
| More detail of all Human literatures about PIM1 | |
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Pathways and Diseases |
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Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Role of Calcineurin-dependent NFAT signaling in lymphocytes;PID Curated;200076 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | Validated targets of C-MYC transcriptional activation;PID Curated;200045 |
Pathway | GMCSF-mediated signaling events;PID Curated;200015 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
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External Links |
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Links to Entrez Gene | 5292 |
Links to all GeneRIF Items | 5292 |
Links to iHOP | 5292 |
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Sequence Information |
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Nucleotide Sequence |
>5292 : length: 942 atgctcttgtccaaaatcaactcgcttgcccacctgcgcgccgcgccctgcaacgacctg cacgccaccaagctggcgcccggcaaggagaaggagcccctggagtcgcagtaccaggtg ggcccgctactgggcagcggcggcttcggctcggtctactcaggcatccgcgtctccgac aacttgccggtggccatcaaacacgtggagaaggaccggatttccgactggggagagctg cctaatggcactcgagtgcccatggaagtggtcctgctgaagaaggtgagctcgggtttc tccggcgtcattaggctcctggactggttcgagaggcccgacagtttcgtcctgatcctg gagaggcccgagccggtgcaagatctcttcgacttcatcacggaaaggggagccctgcaa gaggagctggcccgcagcttcttctggcaggtgctggaggccgtgcggcactgccacaac tgcggggtgctccaccgcgacatcaaggacgaaaacatccttatcgacctcaatcgcggc gagctcaagctcatcgacttcgggtcgggggcgctgctcaaggacaccgtctacacggac ttcgatgggacccgagtgtatagccctccagagtggatccgctaccatcgctaccatggc aggtcggcggcagtctggtccctggggatcctgctgtatgatatggtgtgtggagatatt cctttcgagcatgacgaagagatcatcaggggccaggttttcttcaggcagagggtctct tcagaatgtcagcatctcattagatggtgcttggccctgagaccatcagataggccaacc ttcgaagaaatccagaaccatccatggatgcaagatgttctcctgccccaggaaactgct gagatccacctccacagcctgtcgccggggcccagcaaatag |
Protein Sequence |
>5292 : length: 313 MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA EIHLHSLSPGPSK |