Entrez Gene

Basic Information
Gene ID	5292
Name	PIM1
Synonymous	PIM;pim-1 oncogene;PIM1;pim-1 oncogene
Definition	Oncogene PIM1\|pim-1 kinase 44 kDa isoform\|pim-1 oncogene (proviral integration site 1)\|proto-oncogene serine/threonine-protein kinase pim-1\|serine/threonine-protein kinase pim-1
Position	6p21.2
Gene Type	protein-coding
Gene Regulation:	ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Link to UCSC genome	Matched SNP location	dbSNP ID	Regulatory information
ENCODE RegulomeDB [Top]
chr6:37137979-37143202	chr6:37142422-37142422	rs10507	Single_Nucleotides\|eQTL\|SFRS3, Motifs\|Footprinting\|VDR, Motifs\|PWM\|VDR, Chromatin_Structure\|DNase-seq\|Hah, Chromatin_Structure\|DNase-seq\|Th1, Protein_Binding\|ChIP-seq\|CCNT2, Protein_Binding\|ChIP-seq\|POLR2A, Protein_Binding\|ChIP-seq\|POLR2A, Protein_Binding\|ChIP-seq\|POLR2A, Protein_Binding\|ChIP-seq\|POLR2A, Protein_Binding\|ChIP-seq\|POLR2A, Protein_Binding\|ChIP-seq\|POLR2A

Regulation From TransFac database
Transcription Factors [Top]
CDw338(h) + pim1(h) <==> CDw338(h):pim1(h) (binding)
p27Kip1(h) + pim1(h) <==> p27Kip1(h):pim1(h) (binding)
pim1(h) --/ p27Kip1(h) (decrease of abundance)
pim1(h) + FOXO3a(h) <==> pim1(h):FOXO3a(h) (binding)
pim1(h) --> FOXO3a(h){pT32}{pS253} (increase of phosphorylation)
rps19(h) + pim1(h) <==> rps19(h):pim1(h) (binding)
rps19(h) + pim1(h) <==> rps19(h):pim1(h) (binding)
PIM1(h) --> pim1(h) (expression).
IL-3(m.s.) --> pim1(h) (increase of abundance)
IL-5(m.s.) --> pim1(h) (increase of abundance)
CDw338(h) + ATP --pim1(h)--> CDw338(h){pT362} + ADP (phosphorylation)
p27Kip1(h) + ATP --pim1(h)--> p27Kip1(h){p} + ADP (phosphorylation)
p27Kip1(h) + 2 ATP --pim1(h)--> p27Kip1(h){pT157}{pT198} + 2 ADP (phosphorylation)
mdm2-isoform1(h) + 2 ATP --pim1(h)--> mdm2-isoform1(h){pS166}{pS186} + 2 ADP (phosphorylation)
PRAS40-isoform1(h) + ATP --pim1(h)--> PRAS40-isoform1(h){pT246} + ADP (phosphorylation)
pim1-isoform2(h) --> PRAS40(m){pT247} (increase of phosphorylation)
pim1-isoform2(h) --> 4E-BP1(m){pT36}{pT45} (increase of phosphorylation)
PIM1(h) --> pim1-isoform2(h) (expression).
PIM1(h) --> pim1-isoform1(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for PIM1

ENCODE RegulomeDB [Top]