Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

57142

Name

RTN4

Synonym

ASY|NI220/250|NOGO|NOGO-A|NOGOC|NSP|NSP-CL|Nbla00271|Nbla10545|Nogo-B|Nogo-C|RTN-X|RTN4-A|RTN4-B1|RTN4-B2|RTN4-C;reticulon 4;RTN4;reticulon 4

Definition

Human NogoA|My043 protein|foocen|neurite growth inhibitor 220|neurite outgrowth inhibitor|neuroendocrine-specific protein C homolog|reticulon 5|reticulon-4

Position

2p16.3

Gene Type

protein-coding

PAH Type

Description

PH

The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension.
More detail of all Mouse literatures about RTN4

Pathways and Diseases

Pathway

Signalling by NGF;Reactome;REACT:11061

Disease

Amyotrophic lateral sclerosis;FunDO

Disease

Embryoma;FunDO

Disease

Heart failure;FunDO

Disease

PSYCH;GAD

Disease

Aortic aneurysm;FunDO

Disease

Alzheimer's disease;FunDO

Disease

schizophrenia;GAD

Disease

Multiple sclerosis;FunDO

Disease

Lymphoma;FunDO

Disease

Leukemia;FunDO

Disease

obesity (extreme);GAD

Disease

METABOLIC;GAD

Disease

Schizophrenia;FunDO

Disease

Epilepsy;FunDO

Disease

Depression;FunDO

Disease

Obesity (extreme);NHGRI

Disease

Bipolar disorder;FunDO

External Links

Links to Entrez Gene

57142

Links to all GeneRIF Items

57142

Links to iHOP

57142

Sequence Information

Nucleotide Sequence

>57142 : length: 600
atggacggtcagaagaaaaattggaaggacaaggttgttgacctcctgtactggagagac
attaagaagactggagtggtgtttggtgccagcctattcctgctgctttcattgacagta
ttcagcattgtgagcgtaacagcctacattgccttggccctgctctctgtgaccatcagc
tttaggatatacaagggtgtgatccaagctatccagaaatcagatgaaggccacccattc
agggcatatctggaatctgaagttgctatatctgaggagttggttcagaagtacagtaat
tctgctcttggtcatgtgaactgcacgataaaggaactcaggcgcctcttcttagttgat
gatttagttgattctctgaagtttgcagtgttgatgtgggtatttacctatgttggtgcc
ttgtttaatggtctgacactactgattttggctctcatttcactcttcagtgttcctgtt
atttatgaacggcatcaggcacagatagatcattatctaggacttgcaaataagaatgtt
aaagatgctatggctaaaatccaagcaaaaatccctggattgaagcgcaaagctgaatga

Protein Sequence

>57142 : length: 199
MDGQKKNWKDKVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTIS
FRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVD
DLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNV
KDAMAKIQAKIPGLKRKAE



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