| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 6715 |
Name | SRD5A1 |
Synonym | S5AR 1;steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1);SRD5A1;steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
Definition | 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1|3-oxo-5-alpha-steroid 4-dehydrogenase 1|5-alpha reductase|SR type 1|steroid 5-alpha-reductase 1|steroid 5-alpha-reductase type I |
Position | 5p15 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "catalyzes the conversion of testosterone into the more potent�androgen, dihydrotestosterone (DHT). Personal communication to Dr. Eric D. Austin." |
| More detail of all Human literatures about SRD5A1 | |
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Pathways and Diseases |
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Pathway | Steroid hormone biosynthesis;KEGG PATHWAY;hsa00140 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | androgen biosynthesis;BioCyc;PWY66-378 |
Disease | METABOLIC;GAD |
Disease | hirsutism polycystic ovary syndrome;GAD |
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External Links |
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Links to Entrez Gene | 6715 |
Links to all GeneRIF Items | 6715 |
Links to iHOP | 6715 |
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Sequence Information |
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Nucleotide Sequence |
>6715 : length: 780 atggcaacggcgacgggggtggcggaggagcgcctgctggccgcgctcgcctacctgcag tgcgccgtgggctgcgcggtcttcgcgcgcaatcgtcagacgaactcagtgtacggccgc cacgcgctgcccagccacaggctccgagtgccggcgcgggccgcctgggtggtgcaggag ctgccctcgctggccctgccgctctaccagtacgccagcgagtccgccccgcgtctccgc agcgcgcccaactgcatcctcctggccatgttcctcgtccactacgggcatcggtgctta atttacccatttctgatgcgaggaggaaagcctatgccactgttggcgtgtacaatggcg attatgttctgtacctgtaacggctatttgcaaagcagatacttgagccattgtgcagtg tatgctgatgactgggtaacagatccccgttttctaataggttttggcttgtggttaacg ggcatgttgataaacatccattcagatcatatcctaaggaatctcagaaaaccaggagat actggatacaaaataccaaggggaggcttatttgaatacgtaactgcagccaactatttt ggagaaatcatggagtggtgtggctatgccctggccagctggtctgtccaaggcgcggct tttgctttcttcacgttttgttttttatctggtagagcaaaagagcatcatgagtggtac ctccggaaatttgaagagtatccaaagttcagaaaaattataattccatttttgttttaa |
Protein Sequence |
>6715 : length: 259 MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQE LPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMA IMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGD TGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWY LRKFEEYPKFRKIIIPFLF |