| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 6715 |
Name | SRD5A1 |
Synonymous | S5AR 1;steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1);SRD5A1;steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
Definition | 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1|3-oxo-5-alpha-steroid 4-dehydrogenase 1|5-alpha reductase|SR type 1|steroid 5-alpha-reductase 1|steroid 5-alpha-reductase type I |
Position | 5p15 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
|
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr5:6633456-6669675 | chr5:6638525-6638525 | rs562461 | Single_Nucleotides|eQTL|NSUN2, Single_Nucleotides|eQTL|SRD5A1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|Footprinting|YY1, Motifs|PWM|YY1, Motifs|PWM|YY1, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Nhek, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|DNase-seq|Hpde6e6e7, Chromatin_Structure|FAIRE|Nhek, Chromatin_Structure|DNase-seq|Hmf, Chromatin_Structure|DNase-seq|Hee, Chromatin_Structure|DNase-seq|Hl60, Chromatin_Structure|DNase-seq|Saec, Protein_Binding|ChIP-seq|STAT3, Protein_Binding|ChIP-seq|STAT3, Protein_Binding|ChIP-seq|STAT3 | chr5:6633456-6669675 | chr5:6643847-6643847 | rs166050 | Single_Nucleotides|eQTL|NSUN2, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Fibrobl, Protein_Binding|ChIP-seq|ETS1 | chr5:6633456-6669675 | chr5:6643886-6643886 | rs4702379 | Single_Nucleotides|eQTL|NSUN2, Motifs|PWM|NF-Y, Motifs|PWM|NFYA, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Fibrobl, Protein_Binding|ChIP-seq|ETS1 | chr5:6633456-6669675 | chr5:6645016-6645016 | rs248805 | Single_Nucleotides|eQTL|hCT2250864, Single_Nucleotides|eQTL|NSUN2, Single_Nucleotides|eQTL|SRD5A1, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Hrgec, Chromatin_Structure|DNase-seq|Hmvecdblad, Chromatin_Structure|DNase-seq|Hae, Chromatin_Structure|DNase-seq|Hah, Chromatin_Structure|DNase-seq|Hmvecdblneo, Chromatin_Structure|DNase-seq|Hmveclbl, Chromatin_Structure|DNase-seq|Ag09309, Chromatin_Structure|DNase-seq|Gliobla, Chromatin_Structure|DNase-seq|Hac, Chromatin_Structure|DNase-seq|Hasp, Protein_Binding|ChIP-seq|STAT3, Protein_Binding|ChIP-seq|STAT3 | chr5:6633456-6669675 | chr5:6657808-6657808 | rs248803 | Single_Nucleotides|eQTL|NSUN2, Single_Nucleotides|eQTL|SRD5A1, Motifs|PWM|NF-kappaB(p50), Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Helas3Ifna4h | chr5:6633456-6669675 | chr5:6661323-6661323 | rs248797 | Single_Nucleotides|eQTL|SRD5A1, Protein_Binding|ChIP-seq|RFX3 |
|---|---|---|---|
Transcription Factors [Top] |
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Regulation From TransFac database |
3-oxo-5-alpha-steroid 4-dehydrogenase 1(h) --> SURF-1/SURF-2(h) (DNA binding) | SRD5A1(h) --> 3-oxo-5-alpha-steroid 4-dehydrogenase 1(h) (expression). | SRD5A1(h) --> 3-oxo-5-alpha-steroid 4-dehydrogenase 1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for SRD5A1 | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr5 |
Promoter: 6685000 - 6687000 | GSE27584 |
chr5 |
Promoter: 6685000 - 6687000 | Agilent_014791_44K |