Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6863

Name

TAC1

Synonym

Hs.2563|NK2|NKNA|NPK|TAC2;tachykinin, precursor 1;TAC1;tachykinin, precursor 1

Definition

PPT|neurokinin 1|neurokinin 2|neurokinin A|neurokinin alpha|neuromedin L|neuropeptide K|neuropeptide gamma|preprotachykinin|protachykinin-1|substance K|substance P|tachykinin 2|tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2,

Position

7q21-q22

Gene Type

protein-coding

PAH Type

Description

PH

"Both reactive oxygen species and substance P are involved in perinatal hypoxia-augmented, monocrotaline-induced pulmonary hypertension."
More detail of all Rat literatures about TAC1

Pathways and Diseases

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

Tachykinin receptors bind tachykinins;PID Reactome;500407

Disease

multiple sclerosis;GAD

Disease

IMMUNE;GAD

External Links

Links to Entrez Gene

6863

Links to all GeneRIF Items

6863

Links to iHOP

6863

Sequence Information

Nucleotide Sequence

>6863 : length: 390
atgaaaatcctcgtggccttggcagtcttttttcttgtctccactcagctgtttgcagaa
gaaataggagccaatgatgatctgaattactggtccgactggtacgacagcgaccagatc
aaggaggaactgccggagccctttgagcatcttctgcagagaatcgcccggagacccaag
cctcagcagttctttggattaatgggcaaacgggatgctgattcctcaattgaaaaacaa
gtggccctgttaaaggctctttatggacatggccagatctctcacaaaagacataaaaca
gattcctttgttggactaatgggcaaaagagctttaaattctgtggcttatgaaaggagt
gcaatgcagaattatgaaagaagacgttaa

Protein Sequence

>6863 : length: 129
MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK
PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS
AMQNYERRR



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