| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 960 |
Name | CD44 |
Synonym | CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1;CD44 molecule (Indian blood group);CD44;CD44 molecule (Indian blood group) |
Definition | CD44 antigen|GP90 lymphocyte homing/adhesion receptor|Hermes antigen|cell surface glycoprotein CD44|chondroitin sulfate proteoglycan 8|epican|extracellular matrix receptor III|hematopoietic cell E- and L-selectin ligand|heparan sulfate proteoglycan|homing |
Position | 11p13 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | CD44 and activated T cell infiltration play an important role in the development of plexiform lesions particularly in idiopathic pulmonary arterial hypertension. |
| More detail of all Human literatures about CD44 | |
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Pathways and Diseases |
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Pathway | Alzheimer disease-presenilin pathway;PANTHER;P00004 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | Hematopoietic cell lineage;KEGG PATHWAY;hsa04640 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | ECM-receptor interaction;KEGG PATHWAY;hsa04512 |
Pathway | Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178 |
Disease | Blood group, Indian system;OMIM |
Disease | Cancers;KEGG DISEASE |
Disease | Cancers of the digestive system;KEGG DISEASE |
Disease | Gastric cancer;KEGG DISEASE;H00018 |
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External Links |
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Links to Entrez Gene | 960 |
Links to all GeneRIF Items | 960 |
Links to iHOP | 960 |
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Sequence Information |
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Nucleotide Sequence |
>960 : length: 2229 atggacaagttttggtggcacgcagcctggggactctgcctcgtgccgctgagcctggcg cagatcgatttgaatataacctgccgctttgcaggtgtattccacgtggagaaaaatggt cgctacagcatctctcggacggaggccgctgacctctgcaaggctttcaatagcaccttg cccacaatggcccagatggagaaagctctgagcatcggatttgagacctgcaggtatggg ttcatagaagggcacgtggtgattccccggatccaccccaactccatctgtgcagcaaac aacacaggggtgtacatcctcacatccaacacctcccagtatgacacatattgcttcaat gcttcagctccacctgaagaagattgtacatcagtcacagacctgcccaatgcctttgat ggaccaattaccataactattgttaaccgtgatggcacccgctatgtccagaaaggagaa tacagaacgaatcctgaagacatctaccccagcaaccctactgatgatgacgtgagcagc ggctcctccagtgaaaggagcagcacttcaggaggttacatcttttacaccttttctact gtacaccccatcccagacgaagacagtccctggatcaccgacagcacagacagaatccct gctaccactttgatgagcactagtgctacagcaactgagacagcaaccaagaggcaagaa acctgggattggttttcatggttgtttctaccatcagagtcaaagaatcatcttcacaca acaacacaaatggctggtacgtcttcaaataccatctcagcaggctgggagccaaatgaa gaaaatgaagatgaaagagacagacacctcagtttttctggatcaggcattgatgatgat gaagattttatctccagcaccatttcaaccacaccacgggcttttgaccacacaaaacag aaccaggactggacccagtggaacccaagccattcaaatccggaagtgctacttcagaca accacaaggatgactgatgtagacagaaatggcaccactgcttatgaaggaaactggaac ccagaagcacaccctcccctcattcaccatgagcatcatgaggaagaagagaccccacat tctacaagcacaatccaggcaactcctagtagtacaacggaagaaacagctacccagaag gaacagtggtttggcaacagatggcatgagggatatcgccaaacacccaaagaagactcc cattcgacaacagggacagctgcagcctcagctcataccagccatccaatgcaaggaagg acaacaccaagcccagaggacagttcctggactgatttcttcaacccaatctcacacccc atgggacgaggtcatcaagcaggaagaaggatggatatggactccagtcatagtataacg cttcagcctactgcaaatccaaacacaggtttggtggaagatttggacaggacaggacct ctttcaatgacaacgcagcagagtaattctcagagcttctctacatcacatgaaggcttg gaagaagataaagaccatccaacaacttctactctgacatcaagcaataggaatgatgtc acaggtggaagaagagacccaaatcattctgaaggctcaactactttactggaaggttat acctctcattacccacacacgaaggaaagcaggaccttcatcccagtgacctcagctaag actgggtcctttggagttactgcagttactgttggagattccaactctaatgtcaatcgt tccttatcaggagaccaagacacattccaccccagtggggggtcccataccactcatgga tctgaatcagatggacactcacatgggagtcaagaaggtggagcaaacacaacctctggt cctataaggacaccccaaattccagaatggctgatcatcttggcatccctcttggccttg gctttgattcttgcagtttgcattgcagtcaacagtcgaagaaggtgtgggcagaagaaa aagctagtgatcaacagtggcaatggagctgtggaggacagaaagccaagtggactcaac ggagaggccagcaagtctcaggaaatggtgcatttggtgaacaaggagtcgtcagaaact ccagaccagtttatgacagctgatgagacaaggaacctgcagaatgtggacatgaagatt ggggtgtaa |
Protein Sequence |
>960 : length: 742 MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTL PTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFN ASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSS GSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQE TWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDD EDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWN PEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDS HSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSIT LQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDV TGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNR SLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLAL ALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSET PDQFMTADETRNLQNVDMKIGV |