Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

961

Name

CD47

Synonym

IAP|MER6|OA3;CD47 molecule;CD47;CD47 molecule

Definition

CD47 antigen (Rh-related antigen, integrin-associated signal transducer)|CD47 glycoprotein|Rh-related antigen|antigen identified by monoclonal antibody 1D8|antigenic surface determinant protein OA3|integrin associated protein|integrin-associated protein|i

Position

3q13.1-q13.2

Gene Type

protein-coding

PAH Type

Description

PH

Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.

PH

Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1.
More detail of all Human literatures about CD47

Pathways and Diseases

Pathway

Interactions of the immunoglobulin superfamily (IgSF) member proteins;Reactome;REACT:23853

Pathway

Cell junction organization;Reactome;REACT:20676

Pathway

Cell surface interactions at the vascular wall;PID Reactome;500305

Pathway

Hemostasis;Reactome;REACT:604

Pathway

Integrins in angiogenesis;PID Curated;200109

Pathway

ECM-receptor interaction;KEGG PATHWAY;hsa04512

External Links

Links to Entrez Gene

961

Links to all GeneRIF Items

961

Links to iHOP

961

Sequence Information

Nucleotide Sequence

>961 : length: 972
atgtggcccctggtagcggcgctgttgctgggctcggcgtgctgcggatcagctcagcta
ctatttaataaaacaaaatctgtagaattcacgttttgtaatgacactgtcgtcattcca
tgctttgttactaatatggaggcacaaaacactactgaagtatacgtaaagtggaaattt
aaaggaagagatatttacacctttgatggagctctaaacaagtccactgtccccactgac
tttagtagtgcaaaaattgaagtctcacaattactaaaaggagatgcctctttgaagatg
gataagagtgatgctgtctcacacacaggaaactacacttgtgaagtaacagaattaacc
agagaaggtgaaacgatcatcgagctaaaatatcgtgttgtttcatggttttctccaaat
gaaaatattcttattgttattttcccaatttttgctatactcctgttctggggacagttt
ggtattaaaacacttaaatatagatccggtggtatggatgagaaaacaattgctttactt
gttgctggactagtgatcactgtcattgtcattgttggagccattcttttcgtcccaggt
gaatattcattaaagaatgctactggccttggtttaattgtgacttctacagggatatta
atattacttcactactatgtgtttagtacagcgattggattaacctccttcgtcattgcc
atattggttattcaggtgatagcctatatcctcgctgtggttggactgagtctctgtatt
gcggcgtgtataccaatgcatggccctcttctgatttcaggtttgagtatcttagctcta
gcacaattacttggactagtttatatgaaatttgtggcttccaatcagaagactatacaa
cctcctaggaaagctgtagaggaaccccttaatgcattcaaagaatcaaaaggaatgatg
aatgatgaataa

Protein Sequence

>961 : length: 323
MWPLVAALLLGSACCGSAQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKF
KGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELT
REGETIIELKYRVVSWFSPNENILIVIFPIFAILLFWGQFGIKTLKYRSGGMDEKTIALL
VAGLVITVIVIVGAILFVPGEYSLKNATGLGLIVTSTGILILLHYYVFSTAIGLTSFVIA
ILVIQVIAYILAVVGLSLCIAACIPMHGPLLISGLSILALAQLLGLVYMKFVASNQKTIQ
PPRKAVEEPLNAFKESKGMMNDE



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