Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

240

Name

ALOX5

Synonymous

5-LO|5-LOX|5LPG|LOG5;arachidonate 5-lipoxygenase;ALOX5;arachidonate 5-lipoxygenase

Definition

LOX-5|arachidonic 5-lipoxygenase alpha-10 isoform|arachidonic 5-lipoxygenase delta-10-13 isoform|arachidonic 5-lipoxygenase delta-13 isoform|arachidonic 5-lipoxygenase delta-p10 isoform|arachidonic acid 5-lipoxygenase|leukotriene A4 synthase

Position

10q11.2

Gene Type

protein-coding

Gene Mutation:

GWAS results
PAH samples
Lung cancer

GWAS results   [Top]

There is no record for ALOX5

Lung cancer   [Top]

Mutation (Type; AA; Chr)

Site

Histology

p.E109K; chr10:45878105-45878105

lungadenocarcinoma; carcinoma

p.G93W; chr10:45878057-45878057

lungsquamous_cell_carcinoma; carcinoma

p.M146K; chr10:45907644-45907644

lungadenocarcinoma; carcinoma

p.?; chr10:45869880-45869880

lungadenocarcinoma; carcinoma

p.Q130K; chr10:45891341-45891341

lungadenocarcinoma; carcinoma

p.L642L; chr10:45941036-45941036

lungadenocarcinoma; carcinoma

p.D177Y; chr10:45907736-45907736

lungadenocarcinoma; carcinoma

p.G49G; chr10:45869874-45869874

lungadenocarcinoma; carcinoma

p.R521H; chr10:45938974-45938974

lungadenocarcinoma; carcinoma

p.M146K; chr10:45907644-45907644

lungadenocarcinoma; carcinoma

p.M620K; chr10:45940969-45940969

lungadenocarcinoma; carcinoma

p.T105T; chr10:45878095-45878095

lungsquamous_cell_carcinoma; carcinoma

p.R519L; chr10:45938968-45938968

lungadenocarcinoma; carcinoma

p.G63A; chr10:45877968-45877968

lungadenocarcinoma; carcinoma

p.E209>?; chr10:45919559-45919560

lungadenocarcinoma; carcinoma

p.?; chr10:45935871-45935871

lungadenocarcinoma; carcinoma

p.R667R; chr10:45941109-45941109

lungadenocarcinoma; carcinoma

p.?; chr10:45935871-45935871

lungadenocarcinoma; carcinoma

p.D207N; chr10:45919553-45919553

lungadenocarcinoma; carcinoma


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