| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5740 |
Name | PTGIS |
Synonymous | CYP8|CYP8A1|PGIS|PTGI;prostaglandin I2 (prostacyclin) synthase;PTGIS;prostaglandin I2 (prostacyclin) synthase |
Definition | cytochrome P450, family 8, subfamily A, polypeptide 1|prostacyclin synthase|prostaglandin I2 synthase |
Position | 20q13.13 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
There is no record for PTGIS | ||
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.G435E; chr20:48127619-48127619 |
lung | small_cell_carcinoma; carcinoma |
p.A353D; chr20:48129765-48129765 |
lung | adenocarcinoma; carcinoma |
p.A85A; chr20:48164500-48164500 |
lung | squamous_cell_carcinoma; carcinoma |
p.R93M; chr20:48164477-48164477 |
lung | adenocarcinoma; carcinoma |
p.W88L; chr20:48164492-48164492 |
lung | squamous_cell_carcinoma; carcinoma |
p.G311R; chr20:48130857-48130857 |
lung | adenocarcinoma; carcinoma |
p.T179S; chr20:48156245-48156245 |
lung | adenocarcinoma; carcinoma |
p.?; chr20:48129610-48129610 |
lung | squamous_cell_carcinoma; carcinoma |
p.S116R; chr20:48164407-48164407 |
lung | small_cell_carcinoma; carcinoma |
p.G424W; chr20:48127653-48127653 |
lung | adenocarcinoma; carcinoma |