| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 10891 |
Name | PPARGC1A |
Synonymous | LEM6|PGC-1(alpha)|PGC-1v|PGC1|PGC1A|PPARGC1;peroxisome proliferator-activated receptor gamma, coactivator 1 alpha;PPARGC1A;peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
Definition | L-PGC-1alpha|PGC-1-alpha|PPAR gamma coactivator variant form|PPARGC-1-alpha|ligand effect modulator-6|peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4|peroxisome proliferator-activated receptor gamma coactivator 1 |
Position | 4p15.1 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
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Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr4:23756664-23905712 | chr4:23781649-23781649 | rs2932978 | Single_Nucleotides|eQTL|DHX15, Motifs|PWM|Tcf1, Chromatin_Structure|DNase-seq|Hre, Chromatin_Structure|DNase-seq|Be2c, Chromatin_Structure|DNase-seq|Hmf, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Hrce | chr4:23756664-23905712 | chr4:23884711-23884711 | rs3796407 | Single_Nucleotides|eQTL|PPARGC1A, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Hee, Chromatin_Structure|DNase-seq|Hre, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Hah, Chromatin_Structure|DNase-seq|Hcpe, Chromatin_Structure|DNase-seq|Hac, Chromatin_Structure|DNase-seq|Hnpce, Chromatin_Structure|DNase-seq|Hrce, Chromatin_Structure|DNase-seq|Nha, Chromatin_Structure|DNase-seq|Nhlf, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Saec | chr4:23756664-23905712 | chr4:23890582-23890582 | rs60512528 | Single_Nucleotides|eQTL|PPARGC1A, Chromatin_Structure|DNase-seq|Helas3Ifna4h, Chromatin_Structure|DNase-seq|Aosmc, Chromatin_Structure|DNase-seq|Progfib, Chromatin_Structure|DNase-seq|Panisd, Chromatin_Structure|DNase-seq|Melano, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|DNase-seq|Stellate, Chromatin_Structure|FAIRE|Nhek, Chromatin_Structure|DNase-seq|Hconf, Chromatin_Structure|DNase-seq|Bj, Chromatin_Structure|DNase-seq|Hasp, Chromatin_Structure|DNase-seq|Hgf, Chromatin_Structure|DNase-seq|Hipe, Chromatin_Structure|DNase-seq|Saec, Chromatin_Structure|DNase-seq|Htr8, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|FAIRE|Astrocy, Chromatin_Structure|DNase-seq|Hah, Chromatin_Structure|DNase-seq|Nhdfad, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Hff, Chromatin_Structure|DNase-seq|Hpdlf, Chromatin_Structure|DNase-seq|Gliobla, Chromatin_Structure|DNase-seq|Ag09319, Chromatin_Structure|DNase-seq|Ag10803, Chromatin_Structure|DNase-seq|Hac, Chromatin_Structure|DNase-seq|Hcf, Chromatin_Structure|DNase-seq|Ag04449, Chromatin_Structure|DNase-seq|Hcm, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Hae, Chromatin_Structure|DNase-seq|Hcfaa, Chromatin_Structure|DNase-seq|Aoaf, Chromatin_Structure|DNase-seq|Ag09309, Chromatin_Structure|FAIRE|Nhbe, Chromatin_Structure|DNase-seq|Hpaf, Chromatin_Structure|DNase-seq|Hmf, Chromatin_Structure|DNase-seq|Ag04450, Chromatin_Structure|DNase-seq|Nha, Chromatin_Structure|DNase-seq|Wi38, Chromatin_Structure|DNase-seq|Hvmf, Chromatin_Structure|DNase-seq|Skmc |
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Transcription Factors [Top] |
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Regulation From TransFac database |
PGC-1(h) + HNF-4alpha(h) <==> PGC-1(h):HNF-4alpha(h) (binding). | VDR(h) + PGC-1(h) <==> VDR(h):PGC-1(h) (binding) | T3R-beta1(h) + PGC-1(h) <==> T3R-beta1(h):PGC-1(h) (binding) | FXR(m.s.) + PGC-1(h) <==> FXR(m.s.):PGC-1(h) (binding) | PGC-1(h) + ERR1(h) <==> PGC-1(h):ERR1(h) (binding) | PGC-1(h) --> SLC10A1(h) (transactivation) | PPARGC1A(h) --> PGC-1(h) (expression). | Sox9(r) + PGC-1(h) <==> Sox9(r):PGC-1(h) (binding) | PGC-1(h) + RXR-alpha(h) <==> PGC-1(h):RXR-alpha(h) (binding) | PGC-1(h) --> ESRRA(h) (transactivation) | PXR(h) + PGC-1(h) <==> PXR(h):PGC-1(h) (binding) | PGC-1(h) + ER-beta(h) <==> PGC-1(h):ER-beta(h) (binding) | PGC-1(h) --> Upp1(m) (DNA binding; transactivation). | PPARGC1A(h) --> PGC-1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
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Methylation Profile [Top] | ||
There is no record for PPARGC1A | ||