Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1545

Name

CYP1B1

Synonymous

CP1B|CYPIB1|GLC3A|P4501B1;cytochrome P450, family 1, subfamily B, polypeptide 1;CYP1B1;cytochrome P450, family 1, subfamily B, polypeptide 1

Definition

aryl hydrocarbon hydroxylase|cytochrome P450 1B1|cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase

Position

2p22.2

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

Link to UCSC genome

Matched SNP location

dbSNP ID

Regulatory information

chr2:38294116-38337044chr2:38318940-38318940rs162329Single_Nucleotides|eQTL|CYP1B1, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|FAIRE|Medullo

Transcription Factors   [Top]

Regulation From TransFac database

CYP1B1(h) --> cytochrome P450 1B1(h) (expression).
Aos1(h) + cytochrome P450 1B1(h) <==> Aos1(h):cytochrome P450 1B1(h) (binding)
CYP1B1(h) --> cytochrome P450 1B1(h) (expression).
CYP1B1(h) --> CYP1B1(h) (expression).
hsa-miR-27b --/ CYP1B1(h) (translational repression).

Post Transcriptional Modification   [Top]

There is no record for CYP1B1

Methylation Profile   [Top]

Chromosome

Location

Source

chr2

Promoter: 38156296 - 38158296Agilent_014791

chr2

Promoter: 38156296 - 38158296GoldenGate_Methylation_Cancer_Panel_I

chr2

Promoter: 38156296 - 38158296GSE27584

chr2

Promoter: 38156296 - 38158296Agilent_014791_44K

chr2

Promoter: 38156296 - 38158296PMID:15172987


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