Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

26585

Name

GREM1

Synonymous

CKTSF1B1|DAND2|DRM|GREMLIN|IHG-2;gremlin 1, DAN family BMP antagonist;GREM1;gremlin 1, DAN family BMP antagonist

Definition

DAN domain family member 2|cell proliferation-inducing gene 2 protein|cysteine knot superfamily 1, BMP antagonist 1|down-regulated in Mos-transformed cells protein|gremlin 1, cysteine knot superfamily, homolog|gremlin 1-like protein|gremlin-1|increased in

Position

15q13.3

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for GREM1

Transcription Factors   [Top]

Regulation From TransFac database

BMP2A(h) + Drm(h) <==> BMP2A(h):Drm(h) (binding)
CKTSF1B1(h) --> Drm(h) (expression).
CKTSF1B1(h) --> Drm(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

42N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr15

Promoter: 30795997 - 30797997Agilent_014791

chr15

Promoter: 30795997 - 30797997GSE27584

chr15

Promoter: 30795997 - 30797997PMID:16234815


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