| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 3119 |
Name | HLA-DQB1 |
Synonymous | CELIAC1|HLA-DQB|IDDM1;major histocompatibility complex, class II, DQ beta 1;HLA-DQB1;major histocompatibility complex, class II, DQ beta 1 |
Definition | HLA class II histocompatibility antigen, DQ beta 1 chain|MHC DQ beta|MHC class II DQ beta chain|MHC class II HLA-DQ beta glycoprotein|MHC class II antigen DQB1|MHC class II antigen HLA-DQ-beta-1|MHC class2 antigen|lymphocyte antigen |
Position | 6p21.3 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
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Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr6:32627244-32636160 | chr6:32627386-32627386 | rs12918 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQA1, Motifs|PWM|Freac-3, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32627515-32627515 | rs1056315 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DRB5, Motifs|PWM|CAC-bindingprotein, Chromatin_Structure|FAIRE|Gm19239, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32627714-32627714 | rs1063355 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRA, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Motifs|PWM|Isgf3g, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Gm18507, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|TCF12 | chr6:32627244-32636160 | chr6:32627714-32627714 | rs113823206 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRA, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Motifs|PWM|Isgf3g, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Gm18507, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|TCF12 | chr6:32627244-32636160 | chr6:32627714-32627714 | rs74466734 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRA, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Motifs|PWM|Isgf3g, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Gm18507, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|TCF12 | chr6:32627244-32636160 | chr6:32627714-32627714 | rs77119248 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRA, Single_Nucleotides|eQTL|HLA-DRB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Motifs|PWM|Isgf3g, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Gm18507, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|ELF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|TCF12 | chr6:32627244-32636160 | chr6:32633054-32633054 | rs9274430 | Single_Nucleotides|dsQTL|, Chromatin_Structure|DNase-seq|Nhek, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|H1hesc, Chromatin_Structure|DNase-seq|H9es, Chromatin_Structure|DNase-seq|Saec, Chromatin_Structure|FAIRE|Nhek, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Mcf7, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32633668-32633668 | rs28746828 | Single_Nucleotides|eQTL|HLA-DQA2, Motifs|PWM|Sox18, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|DNase-seq|Gm12865, Chromatin_Structure|DNase-seq|Gm12864, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32634467-32634467 | rs3891175 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQA1, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|T47d, Chromatin_Structure|DNase-seq|Panislets, Chromatin_Structure|DNase-seq|Myometr, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|8988t, Chromatin_Structure|DNase-seq|Nhek, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|DNase-seq|H9es, Chromatin_Structure|FAIRE|Nhek, Chromatin_Structure|DNase-seq|H1hesc, Chromatin_Structure|DNase-seq|Ips, Chromatin_Structure|DNase-seq|Gm18507, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Cll, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Gm19240, Chromatin_Structure|DNase-seq|Gliobla, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|DNase-seq|Progfib, Chromatin_Structure|DNase-seq|Hepatocytes, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|DNase-seq|Urotsa, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Hepg2, Chromatin_Structure|DNase-seq|Htr8, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|Helas3Ifna4h, Chromatin_Structure|DNase-seq|Osteobl, Chromatin_Structure|DNase-seq|Fibrobl, Chromatin_Structure|DNase-seq|Huh75, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|DNase-seq|Panisd, Chromatin_Structure|DNase-seq|Gm06990, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Monocd14, Chromatin_Structure|DNase-seq|Hmvecdneo, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|K562, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|DNase-seq|UrotsaUt189, Chromatin_Structure|FAIRE|Gm12878, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|FAIRE|Htr8, Chromatin_Structure|DNase-seq|Hcm, Chromatin_Structure|DNase-seq|Jurkat, Chromatin_Structure|DNase-seq|Werirb1, Chromatin_Structure|FAIRE|Gliobla, Chromatin_Structure|FAIRE|H1hesc, Chromatin_Structure|DNase-seq|H7es, Chromatin_Structure|DNase-seq|Hipe, Chromatin_Structure|DNase-seq|Hmvecdblad, Chromatin_Structure|DNase-seq|Hmvecdblneo, Chromatin_Structure|DNase-seq|Panc1, Chromatin_Structure|DNase-seq|Hct116, Chromatin_Structure|DNase-seq|Hee, Chromatin_Structure|DNase-seq|Hmveclly, Chromatin_Structure|DNase-seq|Hrce, Chromatin_Structure|DNase-seq|Saec, Chromatin_Structure|DNase-seq|Rptec, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|DNase-seq|Gm12865, Chromatin_Structure|DNase-seq|Hmvecdlyad, Chromatin_Structure|DNase-seq|Hmvecdlyneo, Chromatin_Structure|DNase-seq|Hrgec, Chromatin_Structure|DNase-seq|Be2c, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|RFX5, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|RFX5, Protein_Binding|ChIP-seq|RFX5, Protein_Binding|ChIP-seq|RFX5, Protein_Binding|ChIP-seq|NFYA, Protein_Binding|ChIP-seq|NFYB | chr6:32627244-32636160 | chr6:32635949-32635949 | rs2647025 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQA2, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRA, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|FAIRE|Gm19239, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32635949-32635949 | rs74696845 | Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DQA1, Single_Nucleotides|eQTL|HLA-DQA2, Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DRA, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|FAIRE|Gm19239, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32635974-32635974 | rs3828796 | Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DQA2, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|FAIRE|Gm19239, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr6:32627244-32636160 | chr6:32635974-32635974 | rs78495789 | Single_Nucleotides|eQTL|HLA-DQB1, Single_Nucleotides|eQTL|HLA-DQA2, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Gm12864, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|FAIRE|Gm19239, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A |
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Transcription Factors [Top] |
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Regulation From TransFac database |
HLA-DQB(h) --> HLA-DQB1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for HLA-DQB1 | |||
Methylation Profile [Top] | ||
There is no record for HLA-DQB1 | ||