| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3383 |
Name | ICAM1 |
Synonymous | BB2|CD54|P3.58;intercellular adhesion molecule 1;ICAM1;intercellular adhesion molecule 1 |
Definition | ICAM-1|cell surface glycoprotein P3.58|intercellular adhesion molecule 1 (CD54), human rhinovirus receptor|major group rhinovirus receptor |
Position | 19p13.3-p13.2 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for ICAM1 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
Factor XIIa(h) + icam1(h) <==> Factor XIIa(h):icam1(h) (binding) | CD11B(h):beta2-integrin(h) + icam1(h) <==> CD11B(h):beta2-integrin(h):icam1(h) (binding) | IL-5Rbeta(h) + icam1(h) <==> IL-5Rbeta(h):icam1(h) (binding) | ICAM1(h) --> icam1(h) (expression). | TNF-alpha(m.s.) --> icam1(h) (increase of abundance) | IIP45(h) --/ icam1(h) (decrease of abundance) | LPA1(h) --> icam1(h) (increase of abundance) | GM-CSF(m.s.) --> icam1(h) (increase of abundance) | OPG(h) --> icam1(h) (increase of abundance) | TNF-alpha(h) --> icam1(h) (increase of abundance) | nSMase2(h) --> icam1(h) (increase of abundance) | nSMase3(h) --> icam1(h) (increase of abundance) | thrombin(h) --> icam1(h) (increase of abundance) | Syk(h) --> icam1(h) (increase of abundance) | CD11B(m.s.):beta2-integrin(m.s.) + icam1(h) <==> CD11B(m.s.):beta2-integrin(m.s.):icam1(h) (binding) | icam1(h) + CD11B(h) <==> icam1(h):CD11B(h) (binding) | CD11B(h):beta2-integrin(h) + icam1(h) <==> CD11B(h):beta2-integrin(h):icam1(h) (binding) | LFA-1(h) + icam1(h) <==> LFA-1(h):icam1(h) (binding) | icam1(h) + CD11B(m.s.) <==> icam1(h):CD11B(m.s.) (binding) | alphaL-integrin(h) + icam1(h) <==> alphaL-integrin(h):icam1(h) (binding) | ICAM1(h) --> icam1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
130 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 145 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 183 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 202 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 267 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 296 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 385 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 406 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 501 | Phosphotyrosine | 14973144 | Phospho.ELM 6.0 | 512 | Phosphotyrosine | 14973144 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr19 |
Promoter: 10241279 - 10243279 | Agilent_014791 |
chr19 |
Promoter: 10241279 - 10243279 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 10241279 - 10243279 | GSE27584 |
chr19 |
Promoter: 10241279 - 10243279 | PMID:20064646 |
chr19 |
Promoter: 10241279 - 10243279 | PMID:16242928 |