| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 348 |
Name | APOE |
Synonymous | AD2|LDLCQ5|LPG;apolipoprotein E;APOE;apolipoprotein E |
Definition | apo-E|apolipoprotein E3 |
Position | 19q13.2 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for APOE | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
Abeta40(h) + Apo-E(h) <==> Abeta40(h):Apo-E(h) (binding) | (Abeta40(h))2 + Apo-E(h) <==> (Abeta40(h))2:Apo-E(h) (binding) | Apo-E(h) + Abeta40(m.s.) <==> Apo-E(h):Abeta40(m.s.) (binding) | Apo-E(h) + AGel(h) <==> Apo-E(h):AGel(h) (binding) | alpha2M(h) + Apo-E(h) <==> alpha2M(h):Apo-E(h) (binding) | alpha2M(h) + Apo-E(h) <==> alpha2M(h):Apo-E(h) (binding) | apoE(h) --> Apo-E(h) (expression). | ABC8(h) --> Apo-E(h) (increase of secretion) | 22beta-hydroxycholesterol --> Apo-E(h) (increase of abundance) | TR1 --> Apo-E(h) (increase of abundance) | ApoE3(h) --> Abeta42(h) (increase of secretion) | ApoE3(h) + Tau-F(h) <==> ApoE3(h):Tau-F(h) (binding) | apoE(h) --> ApoE3(h) (expression). | ApoE4(h) + PrP109-141(m.s.) <==> ApoE4(h):PrP109-141(m.s.) (binding) | ApoE4(h) + Abeta40(m.s.) <==> ApoE4(h):Abeta40(m.s.) (binding) | ApoE4(h) + AGel(h) <==> ApoE4(h):AGel(h) (binding) | apoE(h) --> ApoE4(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
212 | O-linked (GalNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for APOE | ||