| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 3552 |
Name | IL1A |
Synonymous | IL-1A|IL1|IL1-ALPHA|IL1F1;interleukin 1, alpha;IL1A;interleukin 1, alpha |
Definition | IL-1 alpha|hematopoietin-1|interleukin-1 alpha|preinterleukin 1 alpha|pro-interleukin-1-alpha |
Position | 2q14 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for IL1A | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
IL-1alpha(h) --> FOSL1(h) (transactivation) | IL-1alpha(h) --> FOS(h) (transactivation) | IL1A(h) --> IL-1alpha(h) (expression). | IL-1alpha(h) --> RelA-p65(m.s.){pS536} (increase of phosphorylation) | IL-1alpha(h) --> IkappaB-alpha(h){pS32} (increase of phosphorylation) | IL-1alpha(h) --> VEGF-A(h) (increase of secretion) | IL-1alpha(h) --> IL-11(h) (increase of secretion) | IL-1alpha(h) --> DEFB4(h) (transactivation) | IL-1alpha(h) --> CCL20(h) (transactivation) | IL-1alpha(h) --/ Tyrp1(h) (decrease of abundance) | IL-1alpha(h) --/ tyrosinase(h) (decrease of abundance) | IL-1alpha(h) --/ L-dopachrome tautomerase(h) (decrease of abundance) | IL-1alpha(h) --> stromelysin1(pg) (increase of abundance) | IL-1alpha(h) --> gelatinase B(pg) (increase of abundance) | IL1A(h) --> IL-1alpha(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
82 | N6-myristoyl lysine. | Swiss-Prot 53.0 | 83 | N6-myristoyl lysine. | Swiss-Prot 53.0 | 102 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 141 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for IL1A | ||