Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4090

Name

SMAD5

Synonymous

DWFC|JV5-1|MADH5;SMAD family member 5;SMAD5;SMAD family member 5

Definition

MAD, mothers against decapentaplegic homolog 5|SMA- and MAD-related protein 5|SMAD, mothers against DPP homolog 5|mothers against decapentaplegic homolog 5|mothers against decapentaplegic, drosophila, homolog of, 5

Position

5q31

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for SMAD5

Transcription Factors   [Top]

Regulation From TransFac database

SMAD5(h) --> Smad5(h) (expression).
HRS(h) + Smad5(h) <==> HRS(h):Smad5(h) (binding)
SMAD5(h) --> Smad5(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

463Phosphoserine.Swiss-Prot 53.0
465Phosphoserine.Swiss-Prot 53.0
128Phosphotyrosine12601080Phospho.ELM 6.0
463Phosphoserine17081983Phospho.ELM 6.0
465Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr5

Promoter: 135494935 - 135496935Agilent_014791

chr5

Promoter: 135494935 - 135496935GSE27584

chr5

Promoter: 135494935 - 135496935GSE27584

chr5

Promoter: 135494935 - 135496935GSE27584

chr5

Promoter: 135494935 - 135496935Agilent_014791_44K


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