| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 4314 |
Name | MMP3 |
Synonymous | CHDS6|MMP-3|SL-1|STMY|STMY1|STR1;matrix metallopeptidase 3 (stromelysin 1, progelatinase);MMP3;matrix metallopeptidase 3 (stromelysin 1, progelatinase) |
Definition | matrix metalloproteinase 3 (stromelysin 1, progelatinase)|matrix metalloproteinase-3|proteoglycanase|stromelysin-1|transin-1 |
Position | 11q22.3 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for MMP3 | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
stromelysin1(h) --> CTGF(h) (DNA binding). | IL-17A(h) --> stromelysin1(h) (activation) | MMP3(h) --> stromelysin1(h) (expression). | IL-17A(h) --> stromelysin1(h) (increase of abundance) | Jak3(h) --> stromelysin1(h) (increase of abundance) | ErbB1(h) --> stromelysin1(h) (increase of abundance) | HB-EGF(h) --stromelysin1(h)--> HB-EGF-ECD(h) + protein remnants (processing; cleavage) | stromelysin1(h) --> CTGF(h) (DNA binding; transactivation). | MMP3(h) --> stromelysin1(h) (expression). | BDNF(r) --stromelysin1(h)--> BDNF-p14(r) + protein remnants (cleavage) |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
120 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for MMP3 | ||