| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 4318 |
Name | MMP9 |
Synonymous | CLG4B|GELB|MANDP2|MMP-9;matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase);MMP9;matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
Definition | 92 kDa gelatinase|92 kDa type IV collagenase|macrophage gelatinase|matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)|matrix metalloproteinase-9|type V collagenase |
Position | 20q11.2-q13.1 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for MMP9 | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
TSP-1(h) + gelatinase B(h) <==> TSP-1(h):gelatinase B(h) (binding) | TSP-2(m) + gelatinase B(h) <==> TSP-2(m):gelatinase B(h) (binding) | 2 gelatinase B(h) <==> (gelatinase B(h))2 (binding; oligomerization) | MMP9(h) --> gelatinase B(h) (expression). | NRG1(m.s.) --> gelatinase B(h) (increase of abundance) | TNF-alpha(h) --> gelatinase B(h) (increase of abundance) | IL-17A(h) --> gelatinase B(h) (increase of abundance) | IL-1beta(m.s.) --> gelatinase B(h) (increase of abundance) | TNF-alpha(m.s.) --> gelatinase B(h) (increase of abundance) | TNF-alpha(m.s.) --> gelatinase B(h) (increase of secretion) | TNF-alpha{sol}(h) --> gelatinase B(h) (increase of secretion) | MMP9(h) --> gelatinase B(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
38 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 120 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 127 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr20 |
Promoter: 44069454 - 44071454 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 44069454 - 44071454 | GSE27584 |