Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5155

Name

PDGFB

Synonymous

PDGF-2|PDGF2|SIS|SSV|c-sis;platelet-derived growth factor beta polypeptide;PDGFB;platelet-derived growth factor beta polypeptide

Definition

PDGF subunit B|PDGF, B chain|becaplermin|platelet-derived growth factor 2|platelet-derived growth factor B chain|platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)|platelet-derived growth factor subunit B|plate

Position

22q13.1

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for PDGFB

Transcription Factors   [Top]

Regulation From TransFac database

PDGFB(h) --> PDGFRbeta(h) (activation)
PDGFB(h) --> PDGFB(h) (expression).
PDGFB(h) --> RhoE(m){pS11} (activation; increase of phosphorylation)
PDGFB(h) --> PDGFB(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for PDGFB

Methylation Profile   [Top]

Chromosome

Location

Source

chr22

Promoter: 37970436 - 37972436Agilent_014791

chr22

Promoter: 37966365 - 37968365Agilent_014791

chr22

Promoter: 37970436 - 37972436GoldenGate_Methylation_Cancer_Panel_I

chr22

Promoter: 37966365 - 37968365GSE27584

chr22

Promoter: 37970436 - 37972436GSE27584

chr22

Promoter: 37970436 - 37972436Agilent_014791_44K


')