| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5156 |
Name | PDGFRA |
Synonymous | CD140A|PDGFR-2|PDGFR2|RHEPDGFRA;platelet-derived growth factor receptor, alpha polypeptide;PDGFRA;platelet-derived growth factor receptor, alpha polypeptide |
Definition | CD140 antigen-like family member A|CD140a antigen|PDGF-R-alpha|PDGFR-alpha|PDGFRA/BCR fusion|alpha-type platelet-derived growth factor receptor|platelet-derived growth factor receptor 2|platelet-derived growth factor receptor alpha|rearranged-in-hypereosi |
Position | 4q12 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for PDGFRA | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
PDGFRalpha(h) + ATP --> PDGFRalpha(h){pY} + ADP (phosphorylation; automodification) | PDGFRA(h) --> PDGFRalpha(h) (expression). | PDGFRA(h) --> PDGFRalpha(h) (expression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
42 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 76 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 103 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 179 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 353 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 359 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 458 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 468 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 849 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 762 | Phosphotyrosine (PDGFR alpha) | 9546424 | Phospho.ELM 6.0 | 754 | Phosphotyrosine (PDGFR alpha) | 7523122 | Phospho.ELM 6.0 | 767 | Phosphoserine | 8617789 | Phospho.ELM 6.0 | 572 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 574 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 720 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 731 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 742 | Phosphotyrosine | 11818394 | Phospho.ELM 6.0 | 1018 | Phosphotyrosine (PDGFR alpha) | 7535778 | Phospho.ELM 6.0 | 988 | Phosphotyrosine (PDGFR alpha) | 7535778 | Phospho.ELM 6.0 | 768 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr4 |
Promoter: 54788704 - 54790704 | Agilent_014791 |
chr4 |
Promoter: 54788704 - 54790704 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 54788704 - 54790704 | Agilent_014791_44K |