Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6348

Name

CCL3

Synonymous

G0S19-1|LD78ALPHA|MIP-1-alpha|MIP1A|SCYA3;chemokine (C-C motif) ligand 3;CCL3;chemokine (C-C motif) ligand 3

Definition

C-C motif chemokine 3|G0/G1 switch regulatory protein 19-1|PAT 464.1|SIS-beta|macrophage inflammatory protein 1-alpha|small inducible cytokine A3 (homologous to mouse Mip-1a)|tonsillar lymphocyte LD78 alpha protein

Position

17q12

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for CCL3

Transcription Factors   [Top]

Regulation From TransFac database

MIP1A(h) --> Cdc42(h) (activation)
CCL3(h) --> MIP1A(h) (expression).
FcgammaRI alpha(h) --> MIP1A(h) (increase of abundance)
MIP1A(h) --cathepsin G(h)--> protein remnants (cleavage)
MIP1A(h) --elastase-2A(h)--> protein remnants (cleavage)
MIP1A(h) --proteinase 3(h)--> protein remnants (cleavage)
MIP1A(h) --> Hck(h){p} (increase of phosphorylation)
MIP1A(h) + CKR-5(h) <==> MIP1A(h):CKR-5(h) (binding)
CCL3(h) --> MIP1A(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for CCL3

Methylation Profile   [Top]

There is no record for CCL3



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