| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 652 |
Name | BMP4 |
Synonymous | BMP2B|BMP2B1|MCOPS6|OFC11|ZYME;bone morphogenetic protein 4;BMP4;bone morphogenetic protein 4 |
Definition | BMP-2B|BMP-4|bone morphogenetic protein 2B |
Position | 14q22-q23 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
|
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr14:54416454-54425479 | chr14:54417522-54417522 | rs17563 | Single_Nucleotides|eQTL|BMP4, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|Hepatocytes, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|8988t | chr14:54416454-54425479 | chr14:54425052-54425052 | rs2761887 | Single_Nucleotides|eQTL|BMP4, Motifs|PWM|YY1, Chromatin_Structure|DNase-seq|Jurkat |
|---|---|---|---|
Transcription Factors [Top] |
|
Regulation From TransFac database |
BMP4(h) + noggin(h) <==> BMP4(h):noggin(h) (binding) | BMP4(h) --> BMP4(h) (expression). | BMP4(h) --> Smad1(h):Nkx3-2(c) (increase of binding) | BMP4(h) --> HDAC1(m.s.):Nkx3-2(c) (increase of binding) | BMP4(h) --> BMP4(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
143 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 208 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 350 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 365 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr14 |
Promoter: 53492862 - 53494862 | Agilent_014791 |
chr14 |
Promoter: 53490520 - 53492520 | Agilent_014791 |
chr14 |
Promoter: 53492862 - 53494862 | GoldenGate_Methylation_Cancer_Panel_I |
chr14 |
Promoter: 53492862 - 53494862 | GoldenGate_Methylation_Cancer_Panel_I |
chr14 |
Promoter: 53492862 - 53494862 | GSE27584 |
chr14 |
Promoter: 53490520 - 53492520 | GSE27584 |
chr14 |
Promoter: 53492862 - 53494862 | GSE27584 |
chr14 |
Promoter: 53490520 - 53492520 | Agilent_014791 |