Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

658

Name

BMPR1B

Synonymous

ALK-6|ALK6|CDw293;bone morphogenetic protein receptor, type IB;BMPR1B;bone morphogenetic protein receptor, type IB

Definition

BMP type-1B receptor|BMPR-1B|activin receptor-like kinase 6|bone morphogenetic protein receptor type-1B|serine/threonine receptor kinase

Position

4q22-q24

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for BMPR1B

Transcription Factors   [Top]

Regulation From TransFac database

BMP2A(h) + BMPR-IB(h) <==> BMP2A(h):BMPR-IB(h) (binding)
AMHR-II(h) + BMPR-IB(h) <==> AMHR-II(h):BMPR-IB(h) (binding)
BMP7(h) + BMPR-II(h) + BMPR-IB(h) <==> BMP7(h):BMPR-II(h):BMPR-IB(h) (binding)
BMPR1B(h) --> BMPR-IB(h) (expression).
Smad1(h) + NTP --BMPR-IB(h)--> Smad1(h){p} + NDP (phosphorylation)
BMPR1B(h) --> BMPR-IB(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for BMPR1B

Methylation Profile   [Top]

Chromosome

Location

Source

chr4

Promoter: 95896651 - 95898651Agilent_014791

chr4

Promoter: 95896651 - 95898651GSE27584

chr4

Promoter: 95896651 - 95898651Agilent_014791_44K


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