| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 659 |
Name | BMPR2 |
Synonymous | BMPR-II|BMPR3|BMR2|BRK-3|PPH1|T-ALK;bone morphogenetic protein receptor, type II (serine/threonine kinase);BMPR2;bone morphogenetic protein receptor, type II (serine/threonine kinase) |
Definition | BMP type II receptor|BMP type-2 receptor|BMPR-2|bone morphogenetic protein receptor type II|bone morphogenetic protein receptor type-2|type II activin receptor-like kinase|type II receptor for bone morphogenetic protein-4 |
Position | 2q33-q34 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
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Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr2:203241659-203432474 | chr2:203290013-203290013 | rs6752522 | Single_Nucleotides|eQTL|BMPR2, Chromatin_Structure|DNase-seq|Hct116, Chromatin_Structure|DNase-seq|Nhlf, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Hrpe, Chromatin_Structure|DNase-seq|Hnpce | chr2:203241659-203432474 | chr2:203315612-203315612 | rs6747756 | Single_Nucleotides|eQTL|BMPR2, Motifs|Footprinting|GR, Motifs|Footprinting|AR, Motifs|Footprinting|GR, Motifs|Footprinting|AR, Motifs|PWM|GR, Motifs|PWM|AR, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Aosmc, Chromatin_Structure|DNase-seq|Ag04450, Chromatin_Structure|DNase-seq|Wi38, Chromatin_Structure|DNase-seq|Nhdfneo, Chromatin_Structure|DNase-seq|Ag09319, Chromatin_Structure|DNase-seq|Hvmf, Protein_Binding|ChIP-seq|AR, Protein_Binding|ChIP-seq|FOXA2, Protein_Binding|ChIP-seq|FOXA1 |
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Transcription Factors [Top] |
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Regulation From TransFac database |
BMP2A(h) + BMPR-II(h) + BMPR-IA(h) <==> BMP2A(h):BMPR-IA(h):BMPR-II(h) (binding) | BMPR-II(h) + BMPR-IA(h) <==> BMPR-IA(h):BMPR-II(h) (binding) | BMPR-IB(m) + BMPR-II(h) <==> BMPR-IB(m):BMPR-II(h) (binding) | BMP2A(h) + BMPR-IB(m) + BMPR-II(h) <==> BMP2A(h):BMPR-IB(m):BMPR-II(h) (binding) | 2 BMPR-II(h) <==> BMPR-II(h):BMPR-II(h) (binding) | BMP2A(h) + BMPR-II(h) <==> BMP2A(h):BMPR-II(h) (binding) | BMP6(h) + ALK-1(h) + BMPR-II(h) <==> BMP6(h):ALK-1(h):BMPR-II(h) (binding) | BMP6(h) + ActR-I(h) + BMPR-II(h) <==> BMP6(h):ActR-I(h):BMPR-II(h) (binding) | BMP6(h) + BMPR-IB(m) + BMPR-II(h) <==> BMP6(h):BMPR-IB(m):BMPR-II(h) (binding) | BMP7(h) + BMPR-II(h) + BMPR-IB(m) + Smad1(h) <==> BMP7(h):BMPR-II(h):BMPR-IB(m):Smad1(h) (binding) | BMP7(h) + BMPR-II(h) + BMPR-IB(m) + Smad5(m) <==> BMP7(h):BMPR-II(h):BMPR-IB(m):Smad5(m) (binding) | BMP7(h) + BMPR-II(h) + BMPR-IB(m) + Smad8(h) <==> BMP7(h):BMPR-II(h):BMPR-IB(m):Smad8(h) (binding) | BMP7(h) + BMPR-IA(h) + BMPR-II(h) <==> BMP7(h):BMPR-IA(h):BMPR-II(h) (binding) | BMP7(h) + BMPR-II(h) + BMPR-IB(h) <==> BMP7(h):BMPR-II(h):BMPR-IB(h) (binding) | BMPR2(h) --> BMPR-II(h) (expression). | BMPR2(h) --> BMPR-II(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
55 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 110 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 126 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 757 | Phosphoserine | 16155937 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr2 |
Promoter: 202948416 - 202950416 | Agilent_014791 |
chr2 |
Promoter: 202948416 - 202950416 | GoldenGate_Methylation_Cancer_Panel_I |
chr2 |
Promoter: 202948416 - 202950416 | GSE27584 |
chr2 |
Promoter: 202948416 - 202950416 | Agilent_014791_44K |