Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6915

Name

TBXA2R

Synonymous

BDPLT13|TXA2-R;thromboxane A2 receptor;TBXA2R;thromboxane A2 receptor

Definition

prostanoid TP receptor

Position

19p13.3

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for TBXA2R

Transcription Factors   [Top]

Regulation From TransFac database

TP(h) --> Gq(v.s.) (activation)
G-alpha-q(h) + TP(h) <==> G-alpha-q(h):TP(h) (binding)
alpha IIb-integrin(h) + TP(h) <==> alpha IIb-integrin(h):TP(h) (binding)
TP(h) + G-alpha(h) <==> TP(h):G-alpha(h) (binding)
PGE2 + TP(h) <==> PGE2:TP(h) (binding)
prostaglandin D2 + TP(h) <==> prostaglandin D2:TP(h) (binding)
prostaglandin F2-alpha + TP(h) <==> prostaglandin F2-alpha:TP(h) (binding)
TBXA2R(h) --> TP(h) (expression).
TPbeta(h) --> Gq(v.s.) (binding)
TPbeta(h) + NDPKB(h) <==> TPbeta(h):NDPKB(h) (binding)
NDPKB(h) + TPbeta(h) <==> NDPKB(h):TPbeta(h) (binding)
TBXA2R(h) --> TPbeta(h) (expression).
TPalpha(h) --> Gq(v.s.) (binding)
TBXA2R(h) --> TPalpha(h) (expression).
GPRASP1(h) + TPalpha-S(h) <==> GPRASP1(h):TPalpha-S(h) (binding)
TBXA2R(h) --> TPalpha-S(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

4N-linked (GlcNAc...).Swiss-Prot 53.0
16N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr19

Promoter: 3557158 - 3559158Agilent_014791

chr19

Promoter: 3557158 - 3559158GSE27584

chr19

Promoter: 3557158 - 3559158GSE27584


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