Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7076

Name

TIMP1

Synonymous

CLGI|EPA|EPO|HCI|TIMP;TIMP metallopeptidase inhibitor 1;TIMP1;TIMP metallopeptidase inhibitor 1

Definition

TIMP-1|collagenase inhibitor|erythroid potentiating activity|erythroid-potentiating activity|fibroblast collagenase inhibitor|metalloproteinase inhibitor 1|tissue inhibitor of metalloproteinases 1

Position

Xp11.3-p11.23

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for TIMP1

Transcription Factors   [Top]

Regulation From TransFac database

TIMP-1(h) + HPXEL(h) <==> TIMP-1(h):HPXEL(h) (binding)
TIMP-1(h) + EF1B(h) <==> TIMP-1(h):EF1B(h) (binding)
TIMP-1(h) + recql5(h) <==> TIMP-1(h):recql5(h) (binding)
TIMP-1(h) --> TIMP-1(h) (expression).
IL-17A(h) --> TIMP-1(h) (increase of abundance)
TIMP-1(h) --> TIMP-1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

Methylation Profile   [Top]

Chromosome

Location

Source

chrX

Promoter: 47325134 - 47327134Agilent_014791

chrX

Promoter: 47325134 - 47327134GoldenGate_Methylation_Cancer_Panel_I

chrX

Promoter: 47325134 - 47327134GSE27584

chrX

Promoter: 47325134 - 47327134PMID:11448064


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