Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	7225
Name	TRPC6
Synonymous	FSGS2\|TRP6;transient receptor potential cation channel, subfamily C, member 6;TRPC6;transient receptor potential cation channel, subfamily C, member 6
Definition	TRP-6\|short transient receptor potential channel 6\|transient receptor protein 6
Position	11q22.1
Gene Type	protein-coding
Gene Regulation:	ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Link to UCSC genome	Matched SNP location	dbSNP ID	Regulatory information
ENCODE RegulomeDB [Top]
chr11:101322295-101743293	chr11:101352427-101352427	rs10895115	Single_Nucleotides\|eQTL\|BIRC2, Chromatin_Structure\|DNase-seq\|Gm12864
chr11:101322295-101743293	chr11:101483577-101483577	rs17676029	Single_Nucleotides\|eQTL\|TRPC6, Motifs\|PWM\|Zfp691, Protein_Binding\|ChIP-seq\|ETS1
chr11:101322295-101743293	chr11:101557676-101557676	rs11224957	Single_Nucleotides\|eQTL\|TRPC6, Chromatin_Structure\|DNase-seq\|Htr8, Chromatin_Structure\|FAIRE\|Htr8, Chromatin_Structure\|DNase-seq\|Hpde6e6e7, Chromatin_Structure\|DNase-seq\|Nhek, Chromatin_Structure\|DNase-seq\|T47d, Chromatin_Structure\|DNase-seq\|Hah, Protein_Binding\|ChIP-seq\|ESR1, Protein_Binding\|ChIP-seq\|ESR1, Protein_Binding\|ChIP-seq\|GATA3
chr11:101322295-101743293	chr11:101588673-101588673	rs17744964	Single_Nucleotides\|eQTL\|TRPC6, Chromatin_Structure\|DNase-seq\|Nhdfneo, Chromatin_Structure\|DNase-seq\|Wi38, Chromatin_Structure\|DNase-seq\|Hgf, Chromatin_Structure\|DNase-seq\|A549

Transcription Factors [Top]
	There is no record for TRPC6

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
70	Phosphothreonine.		Swiss-Prot 53.0
473	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0
561	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0

Chromosome	Location	Source
Methylation Profile [Top]
chr11	Promoter: 100959369 - 100961369	Agilent_014791
chr11	Promoter: 100959369 - 100961369	GSE27584
chr11	Promoter: 100959369 - 100961369	Agilent_014791_44K

')