Entrez Gene

Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)

General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information
Gene ID	7923
Name	HSD17B8
Synonymous	D6S2245E\|FABG\|FABGL\|H2-KE6\|HKE6\|KE6\|RING2\|SDR30C1\|dJ1033B10.9;hydroxysteroid (17-beta) dehydrogenase 8;HSD17B8;hydroxysteroid (17-beta) dehydrogenase 8
Definition	17-beta-HSD 8\|17-beta-hydroxysteroid dehydrogenase 8\|3-oxoacyl-[acyl-carrier-protein] reductase\|estradiol 17-beta-dehydrogenase 8\|estrogen 17-oxidoreductase\|ke-6\|protein Ke6\|really interesting new gene 2 protein\|short chain dehydrogenase/reductase family
Position	6p21.3
Gene Type	protein-coding
Gene Regulation:	ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Link to UCSC genome	Matched SNP location	dbSNP ID	Regulatory information
ENCODE RegulomeDB [Top]
chr6:33172419-33174608	chr6:33173842-33173842	rs113110543	Single_Nucleotides\|eQTL\|NA, Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|PWM\|ARP-1(COUP-TF2), Chromatin_Structure\|DNase-seq\|Hepatocytes, Chromatin_Structure\|DNase-seq\|8988t, Chromatin_Structure\|DNase-seq\|Stellate, Chromatin_Structure\|DNase-seq\|Osteobl, Chromatin_Structure\|FAIRE\|Huvec
chr6:33172419-33174608	chr6:33173842-33173842	rs116493714	Single_Nucleotides\|eQTL\|NA, Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|PWM\|ARP-1(COUP-TF2), Chromatin_Structure\|DNase-seq\|Hepatocytes, Chromatin_Structure\|DNase-seq\|8988t, Chromatin_Structure\|DNase-seq\|Stellate, Chromatin_Structure\|DNase-seq\|Osteobl, Chromatin_Structure\|FAIRE\|Huvec
chr6:33172419-33174608	chr6:33173842-33173842	rs439205	Single_Nucleotides\|eQTL\|NA, Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|Footprinting\|ARP-1(COUP-TF2), Motifs\|PWM\|ARP-1(COUP-TF2), Chromatin_Structure\|DNase-seq\|Hepatocytes, Chromatin_Structure\|DNase-seq\|8988t, Chromatin_Structure\|DNase-seq\|Stellate, Chromatin_Structure\|DNase-seq\|Osteobl, Chromatin_Structure\|FAIRE\|Huvec

Regulation From TransFac database
Transcription Factors [Top]
HSD17B8(h) --> estradiol 17-beta-dehydrogenase 8(h) (expression).
HSD17B8(h) --> estradiol 17-beta-dehydrogenase 8(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for HSD17B8

Methylation Profile [Top]
	There is no record for HSD17B8

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