| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 846 |
Name | CASR |
Synonymous | CAR|EIG8|FHH|FIH|GPRC2A|HHC|HHC1|NSHPT|PCAR1;calcium-sensing receptor;CASR;calcium-sensing receptor |
Definition | extracellular calcium-sensing receptor|parathyroid Ca(2+)-sensing receptor 1|parathyroid cell calcium-sensing receptor |
Position | 3q13 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
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Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr3:121902530-122005342 | chr3:121922253-121922253 | rs7652244 | Single_Nucleotides|eQTL|KPNA1, Chromatin_Structure|DNase-seq|Monocd14 | chr3:121902530-122005342 | chr3:121977125-121977125 | rs10222469 | Single_Nucleotides|eQTL|WDR5B, Motifs|PWM|MEF-2, Motifs|PWM|Elf3, Motifs|PWM|RSRFC4, Protein_Binding|ChIP-seq|NFKB1 | chr3:121902530-122005342 | chr3:121977282-121977282 | rs10934578 | Single_Nucleotides|eQTL|CSTA, Chromatin_Structure|FAIRE|Gm18507, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|NFKB1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|EBF1, Protein_Binding|ChIP-seq|NFKB1 | chr3:121902530-122005342 | chr3:121987619-121987619 | rs11716910 | Single_Nucleotides|eQTL|LOC131076, Motifs|Footprinting|PR=GR, Motifs|PWM|PR=GR, Motifs|PWM|LXR=PXR=CAR=COUP=RAR, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|Gm19240, Chromatin_Structure|DNase-seq|Gm12865, Chromatin_Structure|DNase-seq|Hnpce, Chromatin_Structure|DNase-seq|Hre, Chromatin_Structure|FAIRE|Gm18507, Protein_Binding|ChIP-seq|BCL11A, Protein_Binding|ChIP-seq|MEF2C, Protein_Binding|ChIP-seq|MEF2A | chr3:121902530-122005342 | chr3:121988355-121988355 | rs2202127 | Single_Nucleotides|eQTL|LOC131076, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|DNase-seq|Gm12878 |
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Transcription Factors [Top] |
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Regulation From TransFac database |
CASR(h) --> CaSR-isoform1(h) (expression). | mGluR1a(r) + CaSR(h) <==> mGluR1a(r):CaSR(h) (binding) | mGluR5(r) + CaSR(h) <==> mGluR5(r):CaSR(h) (binding) | CaSR(h) --> VDR(h) (increase of abundance) | CASR(h) --> CaSR(h) (expression). | CASR(h) --> CaSR-isoform2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
90 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 130 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 261 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 287 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 386 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 400 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 446 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 468 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 488 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 541 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 594 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 888 | Phosphothreonine (PKC alpha;PK) | 9694886;12409307 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for CASR | ||