| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 8742 |
Name | TNFSF12 |
Synonymous | APO3L|DR3LG|TWEAK;tumor necrosis factor (ligand) superfamily, member 12;TNFSF12;tumor necrosis factor (ligand) superfamily, member 12 |
Definition | APO3 ligand|APO3/DR3 ligand|TNF-related WEAK inducer of apoptosis|tumor necrosis factor ligand superfamily member 12 |
Position | 17p13 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
|
Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr17:7452208-7464925 | chr17:7454528-7454528 | rs3803796 | Single_Nucleotides|eQTL|LOC400571, Chromatin_Structure|DNase-seq|Hepatocytes |
|---|---|---|---|
Transcription Factors [Top] |
|
Regulation From TransFac database |
TNFSF12(h) --> TWEAK(h) (expression). | TWEAK(h) --/ TRAF2(h) (decrease of abundance) | TWEAK(h) --/ TRAF2(m) (decrease of abundance) | TNFSF12(h) --> TWEAK(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
139 | N-linked (GlcNAc...). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr17 |
Promoter: 7391599 - 7393599 | Agilent_014791 |
chr17 |
Promoter: 7391599 - 7393599 | GSE27584 |