| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 8743 |
Name | TNFSF10 |
Synonymous | APO2L|Apo-2L|CD253|TL2|TRAIL;tumor necrosis factor (ligand) superfamily, member 10;TNFSF10;tumor necrosis factor (ligand) superfamily, member 10 |
Definition | Apo-2 ligand|TNF-related apoptosis inducing ligand TRAIL|chemokine tumor necrosis factor ligand superfamily member 10|tumor necrosis factor (ligand) family, member 10|tumor necrosis factor apoptosis-inducing ligand splice variant delta|tumor necrosis fact |
Position | 3q26 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for TNFSF10 | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
Apo2L(h) + Caspase-10(h) <==> Apo2L(h):Caspase-10(h) (binding) | Apo2L(h) + FADD(h) <==> Apo2L(h):FADD(h) (binding) | Apo2L(h) + proCaspase-8(h) <==> Apo2L(h):proCaspase-8(h) (binding) | 3 Apo2L(h) + 3 DR5(h) <==> (Apo2L(h):DR5(h))3 (binding) | Apo2L(h) + DR5(h) <==> Apo2L(h):DR5(h) (binding) | Apo2L(h) + DR4(v.s.) <==> Apo2L(h):DR4(v.s.) (binding) | Apo2L(h) + DcR1(h) <==> Apo2L(h):DcR1(h) (binding) | Apo2L(h) + OPG(v.s.) <==> Apo2L(h):OPG(v.s.) (binding) | Apo2L(h) + DR4(h) <==> Apo2L(h):DR4(h) (binding) | Apo2L(h) + DCR2(h) <==> Apo2L(h):DCR2(h) (binding) | Apo2L(h) + OPG(h) <==> Apo2L(h):OPG(h) (binding) | Apo2L(h) + DR5(m) <==> Apo2L(h):DR5(m) (binding) | Apo2L(h) + DcTRAIL-R2(m) <==> Apo2L(h):DcTRAIL-R2(m) (binding) | Apo2L(h) + c-FLIP-L(h) <==> Apo2L(h):c-FLIP-L(h) (binding) | Apo2L(h) + c-FLIP-S(h) <==> Apo2L(h):c-FLIP-S(h) (binding) | Caspase-8-p43(h) + Apo2L(h) <==> Caspase-8-p43(h):Apo2L(h) (binding) | Apo2L(h) + Caspase-8-p41(h) <==> Caspase-8-p41(h):Apo2L(h) (binding) | Apo2L(h) + Caspase-10-p44(h) <==> Caspase-10-p44(h):Apo2L(h) (binding) | Apo2L(h) + Caspase-10-p25(h) <==> Caspase-10-p25(h):Apo2L(h) (binding) | proCaspase-8(h) + Apo2L(h) + FADD(h) + DR5(h) <==> proCaspase-8(h):Apo2L(h):FADD(h):DR5(h) (binding) | proCaspase-10(h) + Apo2L(h) + FADD(h) + DR5(h) <==> proCaspase-10(h):Apo2L(h):FADD(h):DR5(h) (binding) | IEX1(h) + Apo2L(h) <==> IEX1(h):Apo2L(h) (binding) | TNFSF10(h) --> Apo2L(h) (expression). | RIP(m.s.) --> Apo2L(h) (activation) | slc5a3(h) --> Apo2L(h) (increase of abundance) | IFNalpha(m.s.) --> Apo2L(h) (increase of abundance) | proCaspase-8a(h) --Apo2L(h)--> Caspase-8a-p20(h) + Caspase-8a-p12(h) + protein remnants (processing) | proCaspase-10B(h) --Apo2L(h)--> Caspase-10a-p17(h) + Caspase-10a-p12(h) + protein remnants (processing) | proCaspase-10A(h) --Apo2L(h)--> Caspase-10b-p20(h) + Caspase-10b-p12(h) + protein remnants (processing) | proCaspase-10d(h) --Apo2L(h)--> Caspase-10d-p20(h) + Caspase-10d-p12(h) + protein remnants (processing) | Apo2L(h) + DR5(h) + FADD(h) + proCaspase-8(h) + c-FLIP-L(h) <==> Apo2L(h):DR5(h):FADD(h):proCaspase-8(h):c-FLIP-L(h) (binding) | Apo2L(h) --> Bid(h) (increase of cleavage) | Apo2L(h) --> Caspase-3-p18(h) (increase of processing) | Apo2L(h) --> proCaspase-8(h) (increase of processing) | Apo2L(h) --> ICAD(h) (increase of cleavage) | DR4(h) + Apo2L(h) <==> DR4(h):Apo2L(h) (binding) | Apo2L(h) + OPG(h) <==> OPG(h):Apo2L(h) (binding) | TNFSF10(h) --> Apo2L(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for TNFSF10 | |||
Methylation Profile [Top] | ||
There is no record for TNFSF10 | ||