| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 9475 |
Name | ROCK2 |
Synonymous | ROCK-II;Rho-associated, coiled-coil containing protein kinase 2;ROCK2;Rho-associated, coiled-coil containing protein kinase 2 |
Definition | p164 ROCK-2|rho-associated protein kinase 2|rho-associated, coiled-coil-containing protein kinase II |
Position | 2p24 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for ROCK2 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
p300(h) + ROCK-II(h) <==> p300(h):ROCK-II(h) (binding) | p300(h) + ROCK-II(h) <==> p300(h):ROCK-II(h) (binding) | IKK-i(h) + ROCK-II(h) <==> IKK-i(h):ROCK-II(h) (binding) | ROCK-II(h) + MPSK(h) <==> ROCK-II(h):MPSK(h) (binding) | ROCK2(h) --> ROCK-II(h) (expression). | ROCK2(h) --> ROCK-II(h) (expression). | MYPT1-isoform1(h) + ATP --ROCK-II(h)--> MYPT1-isoform1(h){pT696}{pT853} + ADP (phosphorylation) |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
1134 | Phosphoserine. | Swiss-Prot 53.0 | 1137 | Phosphoserine. | Swiss-Prot 53.0 | 1362 | Phosphoserine. | Swiss-Prot 53.0 | 1374 | Phosphoserine. | Swiss-Prot 53.0 | 1134 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1137 | Phosphoserine | 15302935 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr2 |
Promoter: 11401662 - 11403662 | Agilent_014791 |
chr2 |
Promoter: 11401662 - 11403662 | GSE27584 |
chr2 |
Promoter: 11401662 - 11403662 | Agilent_014791_44K |
chr2 |
Promoter: 11401662 - 11403662 | Agilent_014791 |