| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 959 |
Name | CD40LG |
Synonymous | CD154|CD40L|HIGM1|IGM|IMD3|T-BAM|TNFSF5|TRAP|gp39|hCD40L;CD40 ligand;CD40LG;CD40 ligand |
Definition | CD40 antigen ligand|CD40-L|T-B cell-activating molecule|T-cell antigen Gp39|TNF-related activation protein|tumor necrosis factor (ligand) superfamily member 5 |
Position | Xq26 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for CD40LG | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
BTLA1(h) + CD154(h) <==> BTLA1(h):CD154(h) (binding) | CD40LG(h) --> CD154(h) (expression). | CD154(h) + CD11B(h):beta2-integrin(h) <==> CD11B(h):beta2-integrin(h):CD154(h) (binding) | CD11B(m.s.):beta2-integrin(m.s.) + CD154(h) <==> CD11B(m.s.):beta2-integrin(m.s.):CD154(h) (binding) | CD154(h) --> HLA-DQ(h) (increase of abundance) | CD154(h) --> LAB72(h) (increase of abundance) | CD154(h) --> BL11(h) (increase of abundance) | CD154(h) --> IL-12(h) (increase of secretion) | CD154(h) --> Il12b(m) (transactivation) | CD154(h) --> TNF-alpha(h) (increase of abundance) | CD154(h) --> IL-6(h) (increase of abundance) | CD154(h) --> irf1(h) (increase of abundance) | CD154(h) --> TAK1(h){pT187} (increase of phosphorylation) | CD154(h) --> IRF1(h) (transactivation) | CD40LG(h) --> CD154(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
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Methylation Profile [Top] | ||
There is no record for CD40LG | ||