Gene Page: PDCD6IP

Summary
GeneID  10015
Symbol  PDCD6IP
Synonyms  AIP1|Alix|DRIP4|HP95|MGC17003
Description  programmed cell death 6 interacting protein
See related  HGNC:8766|MIM:608074|Ensembl:ENSG00000170248|HPRD:06425|
Locus tag  -
Gene type  protein-coding
Map location  3p22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 12.2787 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CRMP10.930.93
MMP240.930.93
PACS10.920.93
SNX260.920.92
FGD10.910.93
GRAMD1A0.900.92
DTX10.900.93
DPYSL50.900.93
DPYSL30.900.95
DOK40.900.93
Top 10 negatively co-expressed genes
HLA-F-0.74-0.78
AF347015.27-0.73-0.85
AF347015.31-0.73-0.85
MT-CO2-0.73-0.86
C5orf53-0.72-0.75
S100B-0.72-0.80
AF347015.33-0.72-0.84
MT-CYB-0.69-0.82
FXYD1-0.69-0.80
AIFM3-0.69-0.70
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityTAS10200558 
GO:0005515protein bindingIPI11883939 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006915apoptosisIEA-
GO:0015031protein transportIEA-
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolTAS9880530 
GO:0005737cytoplasmIEA-
GO:0042470melanosomeIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATN1B37 | D12S755E | DRPLA | NODatrophin 1-HPRD,BioGRID9647693 
CHMP4AC14orf123 | CHMP4 | CHMP4B | HSPC134 | MGC142093 | MGC142095 | SNF7 | SNF7-1 | Shax2chromatin modifying protein 4APDCD6IP (AIP1) interacts with CHMP4A.BIND14505569 
-HPRD12860994 |14583093 
|14678797 
CHMP4A interacts with Alix.BIND14678797 
CHMP4BC20orf178 | CHMP4A | CTPP3 | SNF7 | SNF7-2 | Shax1 | dJ553F4.4chromatin modifying protein 4BCHMP4A interacts with Alix.BIND14678797 
-HPRD12860994 |14678797 
CHMP4CMGC22825 | SNF7-3 | Shax3chromatin modifying protein 4CCHMP4C interacts with Alix.BIND14678797 
-HPRD14678797 
GSTK1GST13glutathione S-transferase kappa 1Affinity Capture-MSBioGRID17353931 
PDCD6ALG-2 | FLJ46208 | MGC111017 | MGC119050 | MGC9123 | PEF1Bprogrammed cell death 6-HPRD,BioGRID9880530 
PHLDA3TIH1pleckstrin homology-like domain, family A, member 3Affinity Capture-MSBioGRID17353931 
SH3GL1CNSA1 | EEN | MGC111371 | SH3D2B | SH3P8SH3-domain GRB2-like 1-HPRD12034747 
SH3GL2CNSA2 | EEN-B1 | FLJ20276 | FLJ25015 | SH3D2A | SH3P4SH3-domain GRB2-like 2-HPRD12034747 
SH3GL3CNSA3 | EEN-2B-L3 | EEN-B2 | HsT19371 | SH3D2C | SH3P13SH3-domain GRB2-like 3-HPRD12034747 
STK24MST-3 | MST3 | MST3B | STE20 | STK3serine/threonine kinase 24 (STE20 homolog, yeast)Affinity Capture-MSBioGRID17353931 
TSG101TSG10 | VPS23tumor susceptibility gene 101PDCD6IP (AIP1) interacts with Tsg101.BIND14505569 
TSG101 interacts with PDCD6IP (AIP-1/ALIX).BIND14519844 
TTF2HuF2transcription termination factor, RNA polymerase IIHuF2 interacts with AIP1.BIND12927788 
-HPRD,BioGRID12927788 
VPS37CFLJ20847vacuolar protein sorting 37 homolog C (S. cerevisiae)Two-hybridBioGRID15509564 
 


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