Gene Page: PARP2

Summary
GeneID  10038
Symbol  PARP2
Synonyms  ADPRT2|ADPRTL2|ADPRTL3|PARP-2|pADPRT-2
Description  poly (ADP-ribose) polymerase 2
See related  HGNC:272|MIM:607725|Ensembl:ENSG00000129484|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2-q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CASC40.740.80
GNS0.730.78
FNDC3A0.720.79
LPIN20.720.80
ANKIB10.720.77
SEC23IP0.720.76
ETS10.720.75
EDEM30.700.77
PCYOX10.700.75
NRXN10.700.77
Top 10 negatively co-expressed genes
MT-CO2-0.51-0.55
AF347015.21-0.51-0.53
FXYD1-0.50-0.47
AF347015.31-0.49-0.53
AF347015.27-0.49-0.50
AF347015.8-0.48-0.53
AF347015.33-0.48-0.47
AC098691.2-0.47-0.55
MT-CYB-0.46-0.48
MYL3-0.46-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003950NAD+ ADP-ribosyltransferase activityIEA-
GO:0003677DNA bindingIEA-
GO:0005515protein bindingIEA-
GO:0016757transferase activity, transferring glycosyl groupsIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006471protein amino acid ADP-ribosylationTAS7260241 
GO:0006284base-excision repairIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BUB3BUB3L | hBUB3budding uninhibited by benzimidazoles 3 homolog (yeast)-HPRD,BioGRID12217960 
CENPACENP-Acentromere protein A-HPRD,BioGRID12217960 
CENPB-centromere protein B, 80kDa-HPRD,BioGRID12217960 
PARP1ADPRT | ADPRT1 | PARP | PARP-1 | PPOL | pADPRT-1poly (ADP-ribose) polymerase 1-HPRD,BioGRID12217960 
XRCC1RCCX-ray repair complementing defective repair in Chinese hamster cells 1Affinity Capture-WesternBioGRID11948190 
 


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