Gene Page: ARPC4

Summary
GeneID  10093
Symbol  ARPC4
Synonyms  ARC20|MGC13544|p20-Arc
Description  actin related protein 2/3 complex, subunit 4, 20kDa
See related  HGNC:707|MIM:604226|Ensembl:ENSG00000214021|HPRD:10368|
Locus tag  -
Gene type  protein-coding
Map location  3p25.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ACP10.860.83
NIPA20.840.78
EIF2AK10.840.79
TTRAP0.840.81
TRMT120.840.80
C20orf430.830.78
PSME30.830.80
AZI20.820.80
ATG120.820.79
HBS1L0.820.79
Top 10 negatively co-expressed genes
AF347015.21-0.69-0.54
MT-CO2-0.69-0.58
AF347015.8-0.68-0.59
AF347015.2-0.68-0.57
AF347015.31-0.66-0.58
AF347015.18-0.66-0.57
MT-CYB-0.66-0.57
AF347015.33-0.65-0.56
AF347015.26-0.64-0.56
AF347015.15-0.64-0.58
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005200structural constituent of cytoskeletonTAS9230079 
GO:0030674protein binding, bridgingTAS11162547 
GO:0051015actin filament bindingTAS11162547 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030041actin filament polymerizationIEA-
GO:0045010actin nucleationTAS11162547 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0042995cell projectionIEAaxon (GO term level: 4)-
GO:0005856cytoskeletonIEA-
GO:0005737cytoplasmIEA-
GO:0005885Arp2/3 protein complexTAS9230079 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTR2ARP2ARP2 actin-related protein 2 homolog (yeast)Arp2/3 complex subunits p20 and Arp2 interactBIND11721045 |11741539 
-HPRD11162547 
ACTR3ARP3ARP3 actin-related protein 3 homolog (yeast)Co-purificationBioGRID11741539 
-HPRD11162547 
Arp2/3 complex subunits p20 and Arp3 interactBIND11741539 
ACTR3BARP11 | ARP3BETA | DKFZp686O24114ARP3 actin-related protein 3 homolog B (yeast)Affinity Capture-MSBioGRID17353931 
ARPC1BARC41 | p40-ARC | p41-ARCactin related protein 2/3 complex, subunit 1B, 41kDa-HPRD9230079 |11162547 
|11721045|11162547 
Arp2/3 complex subunits p41 and p20 interactBIND11741539 
ARPC2ARC34 | PNAS-139 | PRO2446 | p34-Arcactin related protein 2/3 complex, subunit 2, 34kDa-HPRD,BioGRID9230079|11162547 
Arp2/3 complex subunits p34 and p20 interactBIND11721045 |11741539 
ARPC3ARC21 | p21-Arcactin related protein 2/3 complex, subunit 3, 21kDa-HPRD,BioGRID11162547 
-HPRD9000076 
ARPC5ARC16 | MGC88523 | dJ127C7.3 | p16-Arcactin related protein 2/3 complex, subunit 5, 16kDa-HPRD11162547|12451597 
Two-hybridBioGRID11162547 |12451597 
Arp2/3 complex subunits p20 and p16 interactBIND11741539 
ARPC5LARC16-2 | MGC3038actin related protein 2/3 complex, subunit 5-likeTwo-hybridBioGRID16169070 
CTTNEMS1 | FLJ34459cortactinAffinity Capture-MSBioGRID11018051 
TH1LHSPC130 | NELF-C | NELF-D | TH1TH1-like (Drosophila)Two-hybridBioGRID16169070 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1493994061A,m8hsa-miR-149brainUCUGGCUCCGUGUCUUCACUCC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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