Gene Page: ACTR3

Summary
GeneID  10096
Symbol  ACTR3
Synonyms  ARP3
Description  ARP3 actin-related protein 3 homolog (yeast)
See related  HGNC:170|MIM:604222|Ensembl:ENSG00000115091|HPRD:05024|
Locus tag  -
Gene type  protein-coding
Map location  2q14.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0004 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00755 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SCOC0.710.76
AC013275.10.690.73
GLO10.680.71
PARP80.670.71
RFK0.670.69
MMD0.670.71
UBE2E20.670.72
MARCH110.660.71
PSMG10.650.74
COPS40.650.69
Top 10 negatively co-expressed genes
AF347015.18-0.39-0.25
C10orf108-0.35-0.36
AF347015.26-0.34-0.19
AC100783.1-0.33-0.32
ANP32C-0.33-0.35
AC010300.1-0.33-0.36
AC098691.2-0.32-0.27
SMTN-0.32-0.38
AF347015.2-0.32-0.15
AC069281.3-0.32-0.32
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003779actin bindingIEA-
GO:0005515protein bindingIPI17353931 
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006928cell motionTAS9230079 
GO:0030833regulation of actin filament polymerizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0030027lamellipodiumIEA-
GO:0005885Arp2/3 protein complexTAS9230079 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTR2ARP2ARP2 actin-related protein 2 homolog (yeast)Co-purificationBioGRID11741539 
Arp2/3 complex subunits Arp2 and Arp3 interactBIND11721045 |11741539 
ARPC1BARC41 | p40-ARC | p41-ARCactin related protein 2/3 complex, subunit 1B, 41kDaCo-purificationBioGRID11741539 
ARPC2ARC34 | PNAS-139 | PRO2446 | p34-Arcactin related protein 2/3 complex, subunit 2, 34kDa-HPRD9230079 
Co-purificationBioGRID11741539 
Arp2/3 complex subunits p34 and Arp3 interactBIND11741539 
ARPC3ARC21 | p21-Arcactin related protein 2/3 complex, subunit 3, 21kDa-HPRD9000076 
Arp2/3 complex subunits p21 and Arp3 interactBIND11741539 
Co-purificationBioGRID11741539 
ARPC4ARC20 | MGC13544 | p20-Arcactin related protein 2/3 complex, subunit 4, 20kDaCo-purificationBioGRID11741539 
-HPRD11162547 
Arp2/3 complex subunits p20 and Arp3 interactBIND11741539 
CDC42CDC42Hs | G25Kcell division cycle 42 (GTP binding protein, 25kDa)-HPRD9860974 
CDH1Arc-1 | CD324 | CDHE | ECAD | LCAM | UVOcadherin 1, type 1, E-cadherin (epithelial)-HPRD11882288 
CTTNEMS1 | FLJ34459cortactin-HPRD,BioGRID12176742 
EIF1BGC20eukaryotic translation initiation factor 1BAffinity Capture-MSBioGRID17353931 
HCLS1CTTNL | HS1hematopoietic cell-specific Lyn substrate 1Reconstituted ComplexBioGRID12534372 
WASF2SCAR2 | WAVE2 | dJ393P12.2WAS protein family, member 2-HPRD,BioGRID9889097|10381382 
WASF3Brush-1 | KIAA0900 | SCAR3 | WAVE3WAS protein family, member 3-HPRD,BioGRID10381382 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-142-5p8278331Ahsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-145971977m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-190104810551A,m8hsa-miR-190UGAUAUGUUUGAUAUAUUAGGU
miR-38199810041Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
miR-485-5p4734791Ahsa-miR-485-5pAGAGGCUGGCCGUGAUGAAUUC
miR-4861291351Ahsa-miR-486UCCUGUACUGAGCUGCCCCGAG
miR-488108610931A,m8hsa-miR-488CCCAGAUAAUGGCACUCUCAA
miR-4948078131Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.