Gene Page: HCG9
Summary ?
| GeneID | 10255 |
| Symbol | HCG9 |
| Synonyms | HCGIX|HCGIX4 |
| Description | HLA complex group 9 (non-protein coding) |
| Reference | MIM:615797|HGNC:HGNC:21243|Ensembl:ENSG00000204625|HPRD:17092| |
| Gene type | ncRNA |
| Map location | 6p21.3 |
| Pascal p-value | 1E-12 |
| Fetal beta | -0.677 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.033 | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| IQCJ | 0.66 | 0.68 |
| SCHIP1 | 0.65 | 0.68 |
| HSD17B11 | 0.65 | 0.72 |
| PIK3R1 | 0.65 | 0.70 |
| TCEAL1 | 0.64 | 0.70 |
| MKKS | 0.64 | 0.62 |
| SESN1 | 0.63 | 0.62 |
| PEX11B | 0.63 | 0.63 |
| FAM19A2 | 0.63 | 0.69 |
| AP4S1 | 0.63 | 0.64 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.18 | -0.47 | -0.39 |
| AF347015.26 | -0.43 | -0.31 |
| MTSS1L | -0.40 | -0.41 |
| AF347015.2 | -0.39 | -0.27 |
| AC098691.2 | -0.39 | -0.39 |
| MMD2 | -0.39 | -0.36 |
| SORBS3 | -0.39 | -0.41 |
| AC100783.1 | -0.39 | -0.36 |
| SMOX | -0.39 | -0.39 |
| NSBP1 | -0.38 | -0.39 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003674 | molecular_function | ND | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0008150 | biological_process | ND | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005575 | cellular_component | ND | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| BENPORATH EED TARGETS | 1062 | 725 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES WITH H3K27ME3 | 1118 | 744 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |