Gene Page: NET1

Summary
GeneID  10276
Symbol  NET1
Synonyms  ARHGEF8|NET1A
Description  neuroepithelial cell transforming 1
See related  HGNC:14592|MIM:606450|Ensembl:ENSG00000173848|HPRD:07342|
Locus tag  RP11-116G8.1
Gene type  protein-coding
Map location  10p15
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SLC41A30.880.85
C11orf680.870.85
ATP6AP10.870.86
FAM134A0.860.85
GRINA0.860.86
GPAA10.860.86
SLC45A10.850.86
APBB10.850.83
PIGS0.850.81
SCYL10.850.82
Top 10 negatively co-expressed genes
AF347015.18-0.65-0.53
AF347015.21-0.62-0.44
NOSTRIN-0.62-0.50
NSBP1-0.62-0.64
AC098691.2-0.61-0.50
AF347015.8-0.60-0.42
AL139819.3-0.60-0.53
AF347015.26-0.60-0.43
MT-CO2-0.60-0.41
AP002478.3-0.57-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA-
GO:0005085guanyl-nucleotide exchange factor activityTAS8649828 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001558regulation of cell growthNAS8649828 
GO:0007242intracellular signaling cascadeIEA-
GO:0035023regulation of Rho protein signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAGI1AIP3 | BAIAP1 | BAP1 | MAGI-1 | TNRC19 | WWP3membrane associated guanylate kinase, WW and PDZ domain containing 1-HPRD,BioGRID11350080 
RHOAARH12 | ARHA | RHO12 | RHOH12ras homolog gene family, member ATwo-hybridBioGRID9535835 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-132/2121721781Ahsa-miR-212SZUAACAGUCUCCAGUCACGGCC
hsa-miR-132brainUAACAGUCUACAGCCAUGGUCG
miR-1357837901A,m8hsa-miR-135aUAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135bUAUGGCUUUUCAUUCCUAUGUG
miR-1455285351A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-21814561462m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-221501571A,m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
miR-247988041Ahsa-miR-24SZUGGCUCAGUUCAGCAGGAACAG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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