Gene Page: RGS19

Summary
GeneID  10287
Symbol  RGS19
Synonyms  GAIP|RGSGAIP
Description  regulator of G-protein signaling 19
See related  HGNC:13735|MIM:605071|Ensembl:ENSG00000171700|HPRD:05461|
Locus tag  -
Gene type  protein-coding
Map location  20q13.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0859 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
C3orf380.870.87
UBE2D30.860.88
LEPROTL10.860.87
MED210.860.87
CIAPIN10.850.86
IFIT50.850.85
YWHAQ0.850.86
ZNF4100.850.83
LRRC400.850.86
TADA1L0.850.87
Top 10 negatively co-expressed genes
MT-CO2-0.63-0.72
MT-CYB-0.62-0.72
AF347015.26-0.62-0.73
AF347015.33-0.61-0.71
AF347015.8-0.61-0.72
AF347015.31-0.60-0.69
GPT-0.60-0.66
AL132868.3-0.60-0.65
AF347015.2-0.59-0.71
AF347015.27-0.58-0.69
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0005515protein bindingIPI9770488 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007186G-protein coupled receptor protein signaling pathwayTAS8524874 
GO:0009968negative regulation of signal transductionIEA-
GO:0007264small GTPase mediated signal transductionTAS9571244 
GO:0006914autophagyIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusTAS9571244 
GO:0005834heterotrimeric G-protein complexTAS8524874 
GO:0005624membrane fractionTAS9571244 
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GDE1363E6.2 | MIR16glycerophosphodiester phosphodiesterase 1-HPRD10760272 
GIPC1C19orf3 | GIPC | GLUT1CBP | Hs.6454 | IIP-1 | MGC15889 | MGC3774 | NIP | RGS19IP1 | SEMCAP | SYNECTIIN | SYNECTIN | TIP-2GIPC PDZ domain containing family, member 1GAIP interacts with GIPC. This interaction was modelled on a demonstrated interaction between human GAIP and mouse GIPC.BIND11251075 
-HPRD,BioGRID9770488 |11251075 
|11956658 
GNAI1Giguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1-HPRD,BioGRID8986788 |10364213 
GNAI2GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2-HPRD,BioGRID8986788 
GNAI387U6 | FLJ26559guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3-HPRD,BioGRID8524874 |8986788 
GNAO1DKFZp686O0962 | G-ALPHA-o | GNAOguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O-HPRD,BioGRID8986788 
GNAZ-guanine nucleotide binding protein (G protein), alpha z polypeptide-HPRD,BioGRID8986788 
NTRK1DKFZp781I14186 | MTC | TRK | TRK1 | TRKA | p140-TrkAneurotrophic tyrosine kinase, receptor, type 1Affinity Capture-WesternBioGRID11251075 
OPRL1KOR-3 | MGC34578 | NOCIR | OOR | ORL1opiate receptor-like 1-HPRD11090272 
OSTM1GIPN | GL | HSPC019 | OPTB5osteopetrosis associated transmembrane protein 1-HPRD,BioGRID12826607 
 


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