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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: DEF6

Summary

GeneID

50619

Symbol

DEF6

Synonyms

IBP|SLAT

Description

differentially expressed in FDCP 6 homolog (mouse)

Locus tag

RP3-329A5.5

Gene type

protein-coding

Map location

6p21.33-p21.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.033

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.04433

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

GO:0005886

plasma membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
BEGAIN	KIAA1446	brain-enriched guanylate kinase-associated homolog (rat)	Two-hybrid	BioGRID	16189514
CDC42	CDC42Hs \| G25K	cell division cycle 42 (GTP binding protein, 25kDa)	-	HPRD,BioGRID	15023524
CDC42	CDC42Hs \| G25K	cell division cycle 42 (GTP binding protein, 25kDa)	DEF6 interacts with Cdc42. This interaction was modelled on a demonstrated interaction between human DEF6 and Cdc42 from an unspecified species.	BIND	15023524
RAC1	MGC111543 \| MIG5 \| TC-25 \| p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	-	HPRD,BioGRID	15023524
RAC1	MGC111543 \| MIG5 \| TC-25 \| p21-Rac1		DEF6 interacts with Rac1. This interaction was modelled on a demonstrated interaction between human DEF6 and Rac1 from an unspecified species.	BIND	15023524
RAC2	EN-7 \| Gx \| HSPC022	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	DEF6 interacts with Rac2. This interaction was modelled on a demonstrated interaction between human DEF6 and Rac2 from an unspecified species.	BIND	15023524
RAC2	EN-7 \| Gx \| HSPC022		-	HPRD,BioGRID	15023524
RHOA	ARH12 \| ARHA \| RHO12 \| RHOH12	ras homolog gene family, member A	-	HPRD,BioGRID	15023524
RHOA	ARH12 \| ARHA \| RHO12 \| RHOH12	ras homolog gene family, member A	DEF6 interacts with RhoA. This interaction was modelled on a demonstrated interaction between human DEF6 and RhoA from an unspecified species.	BIND	15023524